MULTIVA Calming Helps Pets Keep Calm and Relaxed

Multiva Calming

MULTIVA Calming Supplement

The Multiva Calming supplement is designed to help support balanced behavior and a sense of calm and relaxation for dogs and cats who react to environmental stressors. Each calming chew contains a blend of natural, synergistic ingredients to ease the animal into relaxation without sedation or personality changes. Multiva Calming can be used for specific, challenging events or prolonged management to support both dogs and cats with anxiety and fearfulness. This supplement also helps to reduce the effects of stress on your pet’s health and supports functions of the nervous system and cognitive function.

How MULTIVA Calming may be used to help dogs and cats:

Multiva is suitable for short-term and long-term use, making it ideal for a variety of situations in which dogs and cats may feel stressed or fearful. It may also aid in training and behavior modification to help reduce those commonly associated with stress or anxiety-driven events. These behaviors may vary; some common include hyperactivity, pacing, excessive barking or vocalization, urinating, freezing, panting, aggression, self-harm, or physical injury. While Multiva is labeled for dogs and cats of all ages and breeds, it is generally recommended to talk with your veterinarian before using a new supplement.

  • Thunderstorms, fireworks, loud noises, noise sensitivity, or noise phobias.
  • Veterinary visits, grooming, car trips, vacations, or traveling.
  • Separation anxiety, fearfulness, loneliness,  kenneling or boarding.
  • Changes in social environment: introducing new people or pets,  changes in owner schedule or routines.
  • Changes in physical environment: new furniture, remodeling, construction, or moving.
  • Supports behavior management programs.
  • Aids training and behavior modification.

MULTIVA Calming Ingredients: Multiva contains a blend of key plant and milk-based ingredients that work together to create a calming action. It does not contain sedatives or L-tryptophan. The active ingredients, L-theanine, Colostrum, and Vitamin B1, were chosen and developed by the manufacturer VetNova:

  •  L-Theanine is a naturally occurring amino acid found in green tea. The administration of L-theanine favors states of calmness and relaxation without causing drowsiness,
    reduces episodes of stress, anxiousness, hyperactivity, and irritability, and maintains normal mental alertness, allowing the animal to concentrate and learn.
  • Colostrum has been shown to contain precursors of important neuroactive molecules that can affect alertness, cognitive function, and the level of anxiousness
    in stressed animals. Studies of colostrum given to dogs and cats have shown a reduction in stress and undesired behavioral patterns.
  • Thiamine (Vitamin B1) plays a critical role in the central nervous system, including helping to maintain its normal function, circulation,
    cognitive activity, and brain functions. Thiamine is not stored in the body, and deficiency can occur during stressful situations. Source:

This information is not intended to diagnose or treat any disease and is purely educational. Please seek advice from your pet’s veterinarian with any questions regarding your pet’s health.

Bexacat and Senvelgo: The New Treatments for Cat Diabetes

New Diabetes Medications for Cats

The FDA has approved two new drugs, Bexacat and Senvelgo, to treat diabetes mellitus (high blood sugar) in cats. Unlike traditional insulin shots, these medications are given by mouth, making treatment easier for diabetic cat owners. Bexacat and Senvelgo are a new class of diabetes medication called SGLT2 inhibitors. SGLT2 inhibitors are not insulin, they lower blood glucose by excreting glucose through the kidneys. These medications are prescribed to treat cats that do not require insulin, and they have certain requirements to ensure their safe use.  Learn more about the FDA Approval and safety of Bexacat and Senvelgo.

What is Diabetes Mellitus in Cats?

Diabetes mellitus in cats occurs when the body does not produce enough insulin or is unable to use insulin properly. Insulin is a hormone naturally produced by the pancreas that converts dietary sugar (glucose) to energy for cells in the body. When glucose can’t be used for energy, extra sugar builds up in the blood. High concentrations of sugar in the bloodstream lead to health problems. Certain cats are more prone to diabetes: age, obesity, genetics, certain medications,  and other health conditions are common risks factors. Learn more about Cat Diabetes.

Warning Signs of Diabetes in Cats

  • Increased thirst
  • Increased urination
  • Increased appetite
  • Weight loss
  • Urinary tract infections

Your veterinarian can test and diagnose your cat for diabetes. This may include a general physical exam, blood testing, and urine testing.

Diabetes Treatment Options for Cats

Diabetes is a treatable disease in cats, and symptoms can be managed successfully with regular monitoring. So far, insulin has been the main treatment for diabetes in cats until the recent development and approval of these two new drugs. If your cat has diabetes, it’s important to schedule and keep regular vet check-ups to help spot changes in their condition. Left untreated, this disease leads to serious complications and is fatal.

  • Insulin Injections
  • Medications Bexacat or Senvelgo
  • Blood glucose monitoring
  • Regular check-ups
  • Dietary changes to manage weight and energy needs. This may include therapeutic foods.

Your veterinarian is the best source of information regarding your cat’s medical history and will provide the best treatment choice for your diabetic cat.

  • Bexacat is a flavored tablet containing the active ingredient Bexagliflozin. It is given once daily, with or without food, at the same time to optimize glucose control in cats.
  • It causes sugar to be passed out in the urine by preventing the kidneys from pulling sugar back into the blood.
  • Bexacat is indicated to improve glycemic control in otherwise healthy cats with diabetes mellitus not previously treated with insulin.
  • Senvelgo is a flavored oral solution containing the active ingredient Velagliflozin. It is given once daily by mouth or onto wet food at the same time for optimal glucose control.
  • Senvelgo indicated to improve glycemic control in otherwise healthy cats with diabetes mellitus not previously treated with insulin.
  • This liquid medication does not require refrigeration.

What are SGLT2 Inhibitor Medications for Cats? 

  • The kidneys are your cat’s filtration system for the body. Within the kidneys is a transporter tasked with reabsorbing glucose called sodium-glucose cotransporter 2 (SGLT2). These medications work in the kidneys and prevent the transporter from reabsorbing glucose back into the blood, causing the body to dispose of the glucose in the urine. This process lowers blood glucose levels.
  • Bexacat (bexagliflozin) inhibits SGLT2, a membrane protein found in the kidney that is responsible for reabsorbing most of the glucose from the blood.
  • Senvelgo (velagliflozin) is an SGLT2 inhibitor that reduces blood glucose by preventing the reabsorption of glucose via the SGLT2 cotransporter in the kidney.

Bexacat and Senvelgo Side Effects & Precautions

  • Some cats can’t take Bexacat or Senvelgo. These medications are not meant for cats who have been previously treated with insulin or who are currently on insulin due to the increased risk of developing diabetic ketoacidosis, a severe, life-threatening diagnosis. These medications can be effective in treating diabetes mellitus but are not right for every diabetic cat, especially those with other health problems.

Regular veterinary checkups and careful monitoring are required while your cat is taking Bexacat or Senvelgo. Serious side effects, such as diabetic ketoacidosis and pancreatitis, can happen even in monitored cats with stable blood glucose levels while taking these drugs. For this reason, it’s important to follow your veterinarian’s advice on how to use your cat’s medication and monitor your cat at home. 

  • Common side effects seen with Bexacat and Senvelgo include: vomiting, diarrhea or loose stools, not eating as much or no interest in food, dehydration, lack of energy, continued weight loss, dehydration, increased drinking, increased urination. Report side effects to your veterinarian.

About the Guest Author

This article was contributed and co-authored by VetRxDirect pharmacy intern Gabrielle. “My cat’s name is Cecil, and he enjoys playing fetch with his stuffed star! This photo is Cecil dressed up in costume.” Gabrielle, PharmD Candidate 2024, University of Iowa College of Pharmacy

This information is not intended to diagnose or treat any disease and is purely educational. Please seek advice from your pet’s veterinarian with any questions regarding your pet’s health.

New Visbiome Constipation Care for Cats

Introducing Visbiome Vet Constipation Care! From the makers of our top-selling Visbiome Vet Probiotic Formula, now specially crafted for cats! Visbiome Vet Constipation Care for cats is a high-potency probiotic that relieves occasional constipation in cats and supports natural regularity, proper digestion, and bowel health.

Visbiome Vet Constipation Care for cats may support normal inflammatory responses in the gastrointestinal tract, aid in reducing occasional loose stools due to environmental stress or dietary changes, and may help maintain normal kidney function. Constipation Care is a powder that can be mixed with food or given with paste treats for picky eaters.

Ingredients & Formula

Visbiome Constipation Care at VetRxDirect

Visbiome Vet Constipation Care for cats contains 100 Billion Live Probiotics per packet. It features the slab51® formulation, a blend of eight active probiotic strains. According to the manufacturer, ExeGi Pharma, this high-potency blend was selected due to its individual characteristics and synergistic activities. Learn more.

  • Active Ingredients: 100 billion live bacteria per packet. S. thermophilus DSM32245, L. acidophilus DSM32241, L. plantarum DSM32244, L. paracasei DSM32243, L. helveticus DSM32242, L. brevis DSM27961, B. lactis DSM32246, B. lactis DSM32247.
  • Inactive Ingredients: Maltose, Silicon dioxide.

Cold Shipping & Storage

Like other VisbiomeVet products, Constipation Care is stored and shipped cold to ensure the potency of the live probiotic bacteria are not affected. All orders of VisbiomeVet are shipped from VetRxDirect with a manufacturer provided sensor to guarantee your order did not experience elevated temperatures during shipping. Learn more about Visbiome shipping.

This information is not intended to diagnose or treat any disease and is purely educational. Please seek advice from your pet’s veterinarian with any questions regarding your pet’s health.

Why Heartworm Preventatives Need a Prescription

Heartworm disease is a serious and potentially fatal condition that can affect dogs and cats. The disease is caused by a parasitic worm transmitted through mosquito bites. $500 loan online. Heartworm preventatives are medications designed to prevent this disease by killing the heartworm larvae before they can mature into adult worms.

One thing that may surprise pet owners is that all heartworm prevention for dogs and cats requires a prescription from a veterinarian. Many people wonder why this is the case, and there are several good reasons.

  • Heartworm preventatives are medications designed to be given to dogs and cats for a certain period, usually monthly. Like all medications, they can have side effects and interactions with other medications. By requiring a prescription, veterinarians can ensure that the medication is safe for your dog or cat and that it will not interact with any other medications they may be taking.
  • Heartworm-preventative medications are designed to be effective at specific dosages based on the animal’s weight. Overdosing or underdosing can result in the medication not being effective or causing harm to your dog or cat. By requiring a prescription, veterinarians can ensure the correct dosage is given to each pet.
  •  Heartworm preventatives are prescription medications because they are regulated by the FDA. The FDA regulates all medications, including those for pets, to ensure they are safe and effective. By requiring a prescription, the FDA is able to ensure that heartworm medications are being used in a safe and effective manner.

Why Does my Dog or Cat Need a Heartworm Test?

The American Heartworm Society and most veterinarians recommend an annual heartworm test before prescribing a heartworm preventative. Blood testing ensures that the medication is effective, the pet is not already infected with heartworms, and there are no adverse effects of the medication. Heartworm-preventative medications kill immature heartworm larvae and prevent them from maturing into adults, which causes illness. These medications do not kill adult heartworms.

  • A dog or cat that is infected with heartworms will require a different treatment plan. Starting medication without testing can put the pet at risk of serious complications.
  • Preventatives are highly effective, but your dog or cat can still become infected with heartworms even while taking the medication. Blood testing detects any new infection and allows for prompt treatment.

If you have any questions or concerns about heartworm prevention for your dog or, talk to your veterinarian. They can recommend the best medication for your dog or cat so they receive the best protection from heartworm disease. Learn more about heartworm disease in dogs and cats on our blogs.

This information is not intended to diagnose or treat any disease and is purely educational. Please seek advice from your pet’s veterinarian with any questions regarding your pet’s health. 

New Visbiome Vet Probiotic Packets

Visbiome Vet is Now Available In Packets!

The new Visbiome Vet Probiotic Packets are designed to make dosing for larger animals easier! When it comes to your pet’s diet, one size does not fit all. The larger the pet the more gut support they may need. Visbiome Vet Powder Packets are designed specifically for larger animals. Each packet contains 225 billion CFUs, 2 times the potency of 1 Visbiome Vet capsule.

Visbiome Vet Powder vs Capsules

Now there is no need to pull apart capsules, simply tear open a packet and mix the powder into the pet’s food or water. How is Visbiome Powder this different from the capsules? Visbiome Vet packets are all powder and provide an easier way to administer. The capsules contain 112.5 billion live bacteria and each powder packet contains 225 billion bacteria.

Visbiome Vet Dosing Chart

What is Visbiome Vet Probiotic?

Visbiome Vet is a high potency probiotic formula for dogs and cats. It is made with 8 concentrated strains of live probiotic bacteria, with each capsule containing 112.5 billion bacteria and each powder packet containing 225 billion bacteria. Visbiome assists in reducing occasional loose stools due to environmental stress or dietary changes. It supports the protective layers of the bowel, maintains proper gut flora, and may help manage pets with inflammatory bowel disease. Because it contains live bacteria, Visbiome is stored and shipped cold with temperature monitoring to ensure the highest potency.*

Visbiome Capsules at VetRxDirect
Visbiome Powder Packets at VetRxDirect

Pawsitive Reviews for Visbiome Vet!

Don’t take it from us, check out what other pet parents have to say about Visbiome! With over 400 reviews, This probiotic formula is a top favorite among dog and cat owners and their veterinarians. Many pet parents are sharing stories of improved gut issues, better quality stools, some even describing it as a “game-changer” and “live saver”.

Does your dog or cat take Visbiome? We’d love to hear from you! Leave us a comment below or on our website!

*All orders of VisbiomeVet are shipped with a sensor to guarantee your order did not experience elevated temperatures during shipping. VetRxDirect recommends Next Business Day Shipping to an address with a controlled environment where a person can take immediate possession of the package and refrigerate if you live in an area experiencing ambient outdoor temperatures above 77° F.

This information is not intended to diagnose or treat any disease and is purely educational. Please seek advice from your pet’s veterinarian with any questions regarding the health of your pet. 

Bener ProRed Supports Recovery & Iron Deficiency

Bener™ ProRed by VetNova Animal Health LLC is a new high-strength iron, copper, and multi-vitamin nutritional complex for dogs and cats. Bener ProRed supports intensive recovery care for normal red blood cell, hemoglobin, and iron levels.

Iron is a mineral that our bodies need for many functions. One of the most important roles that iron plays is in the blood. Iron is a part of hemoglobin, a protein in blood that helps carry oxygen from the lungs in the blood through the entire body. Iron is also an essential element for blood production. Usually, dogs and cats obtain enough iron from their diet but they may become low or deficient due to illness, blood loss, poor diet, or an inability to absorb enough iron from foods.

Common Causes of Iron Deficiency Anemia:

  • Blood loss from surgery, injury, or disease
  • Severe intestinal parasite infections
  • Chronic kidney conditions
  • Intestinal conditions or bleeding ulcers
  • Newborns with poor diet

Dogs and cats who are recovering from diseases, surgery, injury, or, physical stress, may benefit from iron-containing supplements. Also pregnant, nursing and active senior animals may also benefit from additional iron support. 

What is Bener ProRed?

Bener™ ProRed is described as an intensive recovery care supplement to support normal red blood cell, hemoglobin, and iron levels in dogs and cats. It provides multiple, essential vitamins and minerals, including a high concentration of iron enhanced by significant levels of Vitamin C. In Bener ProRed, Vitamin C is added to increase the absorption of oral iron. This supplement is ideal for blood donors and helpful for pregnant, nursing, and senior animals. It also adjusts nutritional needs caused by appetite loss and complements homemade diets.Bener ProRed at VetRxDirect

Bener ProRed is a highly palatable, liver-flavored soft chew that comes in two sizes: ProRed-10 and ProRed-30 to complement a wide range of weights. It is usually administered during or after your pet’s meal.

Characteristics of Bener™ ProRed:

  • Complete and balanced formula with 11 nutrients to favor overall health.
  • Rich in iron, copper, and vitamin B complex to support normal red blood cell, hemoglobin, and iron levels.
  • Contains Vitamin C for ideal iron absorption.
  • Contains moderate phosphate levels that do not compromise renal function.

Like other nutritional supplements, it is always important to speak with your veterinarian first to determine if the product is appropriate for your dog or cat’s needs.

This information is not intended to diagnose or treat any disease and is purely educational. Please seek advice from your pet’s veterinarian with any questions regarding the health of your pet. 

Ozloo Veterinary Probiotic Formula for Dogs

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Ozloo is a range of veterinarian formulated probiotic supplements exclusively for dogs. Ozloo supplements help support a healthy gut and maintain intestinal health and balance. They are specially formulated to contain a specific amount of live microorganisms, as well as prebiotics to help support digestive health, including normal flatulence. They also contain Vitamin D to help support bone and skin health.

What makes Ozloo Different from others?Ozloo at VetRxDirect

  • Ozloo believes that no “one size fits all”. That’s why they’ve formulated two different products, one for large breed dogs, and the other for small and medium-breed dogs. Learn more. 
  • Bio-tract Technology: Ozloo also uses proprietary Bio-tract® technology to ensure that your dog gets a steady, even supply of probiotics over 24hrs period to ensure efficacy.

What are the Ingredients?

L. Plantarum and L.Casei are the two strains (species) of probiotics used in Ozloo’s supplements. The product also contains the Prebiotic FOS (Fructooligosaccharides) along with Vitamin D3 which helps support strong bones and support growth & development. Each chewable, sphere-shaped tablet also contains a great tasting, natural pork flavor.

  • Wheat-free
  • Dairy-free
  • Wheat free
  • Gluten-free
  • Non-GMO
  • No artificial colors, flavors, or preservatives

What are Probiotics?

Both people and animals alike have natural microbes or “flora” that naturally live on the lining of their intestines. These are beneficial types of bacterias and yeasts that help digest and absorb nutrients from food. Keeping a healthy balance of good bacteria in the gut is not only important for proper digestion but also for the immune system.

Sometimes beneficial bacteria are damaged or destroyed or diminished. Common reasons include medications, poor diet, disease, or stress. This can also cause your dog’s stomach upset and a general decline in digestive health.

Probiotics are beneficial bacteria that help support gut health and may benefit dogs with gastrointestinal disturbances. Like all dietary supplements, it is best to consult with your veterinarian first to determine if the product best suits your dog’s needs.

 This information is not intended to diagnose or treat any disease and is purely educational. Please seek advice from your pet’s veterinarian with any questions regarding the health of your pet. 

Porus One Kidney Support for Cats

Porus One at VetRx Direct

What is Porus One for Cats?

Porus One is a nutritional supplement used to support kidney health in your cat. It contains Renaltec, a selective carbon that adsorbs protein byproducts. Digestion and metabolism of proteins leads to waste products, which are typically excreted by the kidneys. Взять срочный займ на карту. Porus One binds protein digestion by-products in the intestines so they can be excreted in the feces. This binding process helps to prevent the byproducts from being converted into uremic toxins, which supports kidney health.

How Does Porus One Help with Uremic Toxins?

  • Cats eat proteins in their diet on a daily basis. When proteins are metabolized in the body, waste products called uremic toxins naturally form. These toxins are then filtered out by the kidneys and excreted in the urine.
  • When a cat’s kidneys no longer function as well as before, they filter out fewer uremic toxins. As a result, the toxins may accumulate in the body and cause damage to the kidneys and other organs.
  • Porus One adorbs toxins while they are still in the intestine and passes them out of the body in the feces. As a result, the toxins do not enter the kidneys and cannot accumulate in the body. This also helps reduce the workload on the kidneys.

What is it made of?

Porus One contains Renaltec®, a pure carbon that is shaped into tiny spheres in a patented production process. Renaltec absorbs protein byproducts (uremic toxins) in the gut so they can be excreted in feces instead of the kidneys.

How To Use Porus One

Porus® One is easily mixed in with your cat’s wet or dry food. It is tasteless and odorless and generally well tolerated by cats.

This supplement may be used for cats with reduced kidney function or types of kidney disease or disorders. Like any supplement, it is always best to consult with your veterinarian to determine if the product best suit’s your cat’s needs. Your veterinarian is the best source of medical information for your cat.

This information is not intended to diagnose or treat any disease and is purely educational. Please seek advice from your pet’s veterinarian with any questions regarding the health of your pet. 

Elura Approved for Weight Loss in Cats

The U.S. Food and Drug Administration has approved Elura (capromorelin oral solution) as the first drug for the management of weight loss in cats with chronic kidney disease.

Chronic kidney disease, also known as CKD, is the persistent loss of kidney function over time. Cats with chronic kidney disease may begin to lose weight before getting diagnosed by a veterinarian and typically continue to lose weight as the disease progresses.Elura at VetRxDirect

Capromorelin, the active ingredient in Elura, provides a novel mechanism of action to address weight loss in cats with CKD. It stimulates appetite and the secretion of growth hormone. Weight gain in cats taking Elura is thought to be due to a combination of increased food intake and metabolic changes.

Capromorelin is also approved as Entyce for appetite stimulation in dogs. Elura is the second product that the FDA has approved for the management of unintended weight loss in cats. The first product, Mirataz, is an appetite stimulant applied topically to the skin. Learn more about the approval of Elura.

Signs of Weight Loss in Cats

It is important to keep an eye on your cat’s eating habits and observe any changes in their body condition while holding or petting them. Report these changes to your veterinarian.

  •  Reduced interest in food
  • Changes in the amount eaten
  • An increased amount of time taken to eat
  • Bony protrusions or ribs
  • Tender spots
  • Lumps or bumps

If you are concerned about your cat’s weight loss, speak with your veterinarian about treatment options.

This information is not intended to diagnose or treat any disease and is purely educational. Please seek advice from your pet’s veterinarian with any questions regarding the health of your pet. 

Cardalis for Dogs with Congestive Heart Failure

The U.S. Food and Drug Administration (FDA) has announced the approval of Cardalis for managing congestive heart failure in dogs. Cardalis contains spironolactone and benazepril in a chewable tablet. Spironolactone is a potassium-sparing diuretic type medication that helps remove excess salt and fluid from the body and prevents potassium levels from getting too low. Benazepril is an ACE Inhibitor type medication that lowers blood pressure by relaxing veins and arteries.Cardalis at VetRxDirect

When used with other medications, Cardalis is approved to manage the symptoms of mild, moderate, or severe congestive heart failure in dogs due to atrioventricular valvular insufficiency (AVVI). AVI is a form of heart disease in dogs that can lead to congestive heart failure.

What is Congestive Heart Failure?

AVVI commonly occurs in older dogs typically over the age of 8 years and smaller breed dogs. When dogs suffer from heart failure, their hearts are unable to pump sufficient blood to the rest of the organs in the dog’s body. In congestive heart failure, blood backs up in organs and causes them to function abnormally, become swollen with fluid, or both. The most common signs of congestive heart failure include, but are not limited to:

  • Persistent coughing
  • Difficulty breathing
  • Reduced energy & stamina
  • Excessive panting
  • Swollen abdomen
  • Restlessness
  • Pale or bluish gums
  • Loss of appetite
  • Weight loss and/or muscle wasting


As with any heart problem, diagnosing congestive heart failure requires a thorough exam from a veterinarian and typically involves multiple tests. Although heart failure is a chronic disease, it can be medically managed with early diagnosis and a veterinarian-guided treatment plan.


It is important to treat heart failure in order to improve heart performance, control arrhythmias, and blood pressure, and improve blood flow. All of these can further damage the heart and blood vessels if not controlled.

Why is Cardalis New?

Human-approved benazepril and spironolactone have been used extra-label to treat AVVI in dogs. With this approval, the FDA has determined the combination of drugs in Cardalis is safe and effective for dogs. Learn more.

What Should I Know about Cardalis?

The safety and effectiveness of Cardalis were demonstrated in a 12-month field study in the United States involving 569 dogs. Cardalis requires a prescription because a veterinarian is needed to diagnose congestive heart failure in dogs due to AVVI, design an appropriate treatment plan, and monitor the safe use of the medication.