Q & A

• My dog is currently on 30 twice a day of Vetoryl. What amount of the compounded tablets would he need daily??

  Asked by Christina
  4 years ago

  • Compounded Trilostane is no longer available at our pharmacy. We apologize for the inconvenience.

    Holly
    Verified Answer

• My 30 pound Whippet has been taking 10mg vetoryl 2 times daily. What would be the conversion and dosage if I were to request the trilostane suspension??

  Asked by Robin
  5 years ago

  • The Trilostane (Compounded) suspension is a corn oil based, liquid suspension containing the contents of the Vetoryl Capsules and formulated to the strengths listed on the VetRxDirect home page. As an example, the Trilostane (Compounded) 5mg/ml suspension would require a dose of 2ml twice daily, to be equivalent in dose to a 10mg Vetoryl capsule, twice daily. The oil based Trilostane (Compounded) suspension does not require refrigeration, does require shaking prior to each use and has a beyond-use-date (date at which the product should no longer be used) of 90 days from the date of compounding. Please speak with your veterinarian to determine if a suspension dosage form of trilostane would be appropriate for your dog

    VetRxDirect
    Verified Answer

• If my dog is currently taking 30 mg vetoryl, What would the liquid dosage be if we switched? Trying to compare price if we change?

  Asked by melody
  5 years ago

  • There is a Trilostane 30 mg/mL concentration available, so if your dog is needing 30 mg daily then it would be 1 mL daily with the compounded product. Please check on the VetRxDirect website for current pricing for this product.

    VetRxDirect
    Verified Answer

• How much would it cost to get 180 of Trilostane 6mg capsules??

  Asked by Shirley
  6 years ago

  • Please use the 'Select Product' drop down and 'Enter Quantity' of 360 of the 3mg capsules. Please confirm the exact dose needed for your dog with your veterinarian.

    VetRxDirect
    Verified Answer

• Is it okay to plan on a 0.2mL (i.e. 0.2mL of 50mg/mL for 10mg dose) or will it be too difficult to measure and administer this amount??

  Asked by Shane
  8 years ago

  • This should be difficult to measure as we will give you a syringe with the appropriate markings to measure this amount accurately.

    Verified Answer

• Is this drug compounded from an FDA approved source such as Vetoryl ? Is the compounded Trilostane FDA approved just like Vetoryl ??

  Asked by Les
  8 years ago

  • Vetoryl is a FDA approved product for the the treatment of hyperadrenocorticism. Compounding trilostane allows for a pharmacist to create a medication that is tailored to the specialized needs of an individual pet according to a veterinarian's prescription. The FDA does recognize that compounding plays an important role in tailoring medications to meet the needs of a patient/pet. Trilostane is compounded by VetRxDirect's expert compounding staff and is available in many dosage forms to tailor to your pet's needs. It would be important to contact your pet's veterinarian to see if compounded trilostane would be a good option for your pet.

    Verified Answer

• does this product come in liquid form?..........how administered? how do you determine mg dosage? Thanks!?

  Asked by Richard
  8 years ago

  • VetRxDirect offers trilostane in a capsule formulation under the brand name "Vetoryl." It is available in a variety of strengths including 5mg, 10mg, 30mg, and 60mg capsules. In addition, trilostane is also available through VetRxDirect as a compounded capsule formulation. This may be a suitable option for you if your pet's required dose is not commercially available. The medication is administered to the pet by mouth, often in some food or a treat to make it more appealing and palatable. The appropriate strength is dependent upon many factors such as diagnosis, species, concurrent medications, and weight. Please consult your pet's veterinarian to determine which strength would best suit your pet's needs. Thank you, VetRxDirect

    Verified Answer

• Hi! I was wondering what you used to suspend the trilostane? Is it oil or water-based??

  Asked by Erica
  8 years ago

  • The trilostane suspension is an oil based suspension with silica gel used to suspend the active drug. VetRxDirect places a 90 beyond use date, or the date on which the suspension should no longer be used, after compounding. Thank you, VetRxDirect

    Verified Answer

• Can the oral suspension of Trilostane cause teeth deterioration? I've noticed since I've been giving my 93# dog the medicine since the end of October, his teeth have gotten quite brown. Gums are red as well. They were pretty white prior.?

  Asked by Balloo
  10 years ago

  • The most common adverse effects seen with trilostane use are lethargy, weakness, loss of appetite for a fews day, vomiting and diarrhea. I am unable to find any medical literature associating teeth or tongue discoloration or deterioration with the use of trilostane. I recommend contacting your veterinarian to determine the cause of this. Thank you, VetRxDirect

    VetRxDirect
    Community Answer

• My 11 year old 54 lb dog has been on a 2 x daily dosage of 0.5 liquid trilostane for 17 days.  She is still exhibiting symptoms of Cushings including excessive drinking, urination, panting at rest and increased appetite. How long before she improves??

  Asked by Gracie11
  10 years ago

  • Trilostane is a common treatment for dogs with high cortisol levels or Cushing’s disease. The starting dose of the medication is determined by the weight of the pet and then adjusted according to the cortisol levels and clinical symptoms. Cortisol levels are typically checked 10-14 days after beginning treatment and the dose is then adjusted accordingly. Reaching the optimum dose to control symptoms and reduce side effects may take several dose adjustments. It is important to follow up with all appointments. It may be beneficial to contact your veterinarian and report your dogs continued clinical symptoms after 17 days of treatment. Thank you, VetRxDirect

    VetRxDirect
    Community Answer