My 30 pound Whippet has been taking 10mg vetoryl 2 times daily. What would be the conversion and dosage if I were to request the trilostane suspension?

The Trilostane (Compounded) suspension is a corn oil based, liquid suspension containing the contents of the Vetoryl Capsules and formulated to the strengths listed on the VetRxDirect home page. As an example, the Trilostane (Compounded) 5mg/ml suspension would require a dose of 2ml twice daily, to be equivalent in dose to a 10mg Vetoryl capsule, twice daily. The oil based Trilostane (Compounded) suspension does not require refrigeration, does require shaking prior to each use and has a beyond-use-date (date at which the product should no longer be used) of 90 days from the date of compounding. Please speak with your veterinarian to determine if a suspension dosage form of trilostane would be appropriate for your dog

If my dog is currently taking 30 mg vetoryl, What would the liquid dosage be if we switched? Trying to compare price if we change

There is a Trilostane 30 mg/mL concentration available, so if your dog is needing 30 mg daily then it would be 1 mL daily with the compounded product. Please check on the VetRxDirect website for current pricing for this product.

How much would it cost to get 180 of Trilostane 6mg capsules?

Please use the 'Select Product' drop down and 'Enter Quantity' of 360 of the 3mg capsules. Please confirm the exact dose needed for your dog with your veterinarian.

Is it okay to plan on a 0.2mL (i.e. 0.2mL of 50mg/mL for 10mg dose) or will it be too difficult to measure and administer this amount?

This should be difficult to measure as we will give you a syringe with the appropriate markings to measure this amount accurately.

Is this drug compounded from an FDA approved source such as Vetoryl ? Is the compounded Trilostane FDA approved just like Vetoryl ?

Vetoryl is a FDA approved product for the the treatment of hyperadrenocorticism. Compounding trilostane allows for a pharmacist to create a medication that is tailored to the specialized needs of an individual pet according to a veterinarian's prescription. The FDA does recognize that compounding plays an important role in tailoring medications to meet the needs of a patient/pet. Trilostane is compounded by VetRxDirect's expert compounding staff and is available in many dosage forms to tailor to your pet's needs. It would be important to contact your pet's veterinarian to see if compounded trilostane would be a good option for your pet.

does this product come in liquid form?..........how administered? how do you determine mg dosage? Thanks!

VetRxDirect offers trilostane in a capsule formulation under the brand name "Vetoryl." It is available in a variety of strengths including 5mg, 10mg, 30mg, and 60mg capsules. In addition, trilostane is also available through VetRxDirect as a compounded capsule formulation. This may be a suitable option for you if your pet's required dose is not commercially available. The medication is administered to the pet by mouth, often in some food or a treat to make it more appealing and palatable. The appropriate strength is dependent upon many factors such as diagnosis, species, concurrent medications, and weight. Please consult your pet's veterinarian to determine which strength would best suit your pet's needs. Thank you, VetRxDirect

Hi! I was wondering what you used to suspend the trilostane? Is it oil or water-based?

The trilostane suspension is an oil based suspension with silica gel used to suspend the active drug. VetRxDirect places a 90 beyond use date, or the date on which the suspension should no longer be used, after compounding. Thank you, VetRxDirect

Can the oral suspension of Trilostane cause teeth deterioration? I've noticed since I've been giving my 93# dog the medicine since the end of October, his teeth have gotten quite brown. Gums are red as well. They were pretty white prior.

The most common adverse effects seen with trilostane use are lethargy, weakness, loss of appetite for a fews day, vomiting and diarrhea. I am unable to find any medical literature associating teeth or tongue discoloration or deterioration with the use of trilostane. I recommend contacting your veterinarian to determine the cause of this. Thank you, VetRxDirect

My 11 year old 54 lb dog has been on a 2 x daily dosage of 0.5 liquid trilostane for 17 days. She is still exhibiting symptoms of Cushings including excessive drinking, urination, panting at rest and increased appetite. How long before she improves?

Trilostane is a common treatment for dogs with high cortisol levels or Cushing’s disease. The starting dose of the medication is determined by the weight of the pet and then adjusted according to the cortisol levels and clinical symptoms. Cortisol levels are typically checked 10-14 days after beginning treatment and the dose is then adjusted accordingly. Reaching the optimum dose to control symptoms and reduce side effects may take several dose adjustments. It is important to follow up with all appointments. It may be beneficial to contact your veterinarian and report your dogs continued clinical symptoms after 17 days of treatment. Thank you, VetRxDirect

Trilostane (Compounded)

Compounded Trilostane for Cushing’s Disease in Dogs

Trilostane (Compounded) ^Rx

44 Reviews

15 Answered Questions

We're sorry, this product is no longer available.

Out of Stock

Compounded Trilostane is no longer available at our pharmacy. We apologize for the inconvenience.

Compounded Trilostane Oral Suspension

Trilostane is a prescription medication used to treat Cushing’s Disease, or hyperadrenocorticism in dogs and cats. Trilostane is an adrenocortical suppressant which prevents the adrenal gland from producing too much cortisol. Cushing’s Disease is a disorder where the body produces too much cortisol hormone. Trilostane is compounded by the VetRxDirect pharmacy in an oral suspension.

Read and follow the prescription label carefully for storage information, possible side effects, and drug interactions.
Give the exact amount prescribed and only as often as directed.
Do not skip doses or stop giving the medication without consulting your veterinarian.

Beyond Use Date for Compounded Trilostane:

Due to the shelf life of this medication, it is recommended that Trilostane Suspension be used within 80 days.

What else should you know about compounded trilostane liquid:

Trilostane suspensions are compounded by our expert compounding staff at VetRxDirect. It is important to order your refills a few days ahead of time because the product needs to be made for your pet. Shake the suspension well before each time you draw up your pet’s dose.

Review Summary

44 total reviews

Rated 4.86 out of 5 stars

100% of respondents would recommend this to a friend

Ratings Distribution

38 5 star reviews

6 4 star reviews

0 3 star reviews

0 2 star reviews

0 1 star reviews

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Reviews

Fast, reliable service with good follow-up

Rated 5 out of 5 stars
9 years ago
By ggd1

From San Antonio, TX, USA

Comments about Trilostane (Compounded)

My 10-year old Maltapoo recently was diagnosed with Cushings disease; she was prescribed 5mgTrilostane BID. The medication arrived promptly and Sophie is having a positive response: less compulsive water consumption and less frequent urination (less accidents). I was impressed with VetRxDirect's service and prices.
Good product

Rated 4 out of 5 stars
10 years ago
By Bijoux

From Austin, TX, USA

Comments about Trilostane (Compounded)

Return customer and process is easy. Just make sure you order a week in advance. Turn around time is not very fast
Great company! Best deal on trilostane!

Rated 5 out of 5 stars
10 years ago
By JMarleyboo

From New Jersey, USA

Comments about Trilostane (Compounded)

My dog sammie needed 90 mg of Trilostane twice a day. The pills are not generally available in this strength so I had to purchase 60 and 30 mg pills separately. Before I found Vetrxdirect, the medication was costing me over $300.00 a month. Vetrxdirect is able to compound the medication for me in the required 90 mg dosage per pill. I am saving over $100.00 a month with Vetrxdirect. They are very professional. Ordering and shipping is fast and easy. They contact my Vet directly for refills, saving me time. The medication to treat my Sammies Cushings disease is so expensive so I am very thankful for the savings I am getting from Vetrxdirect. I also get Thyroid medication for Sammie and my other dog Trapper at a substantial savings. I would recommend Vetrxdirect to anyone.
Compounded Trilostane works well

Rated 5 out of 5 stars
10 years ago
By btag

From Micco, FL

Comments about Trilostane (Compounded)

3 days after starting, Sage had an ACTH blood test. First time she has been close to the correct number. We are so happy. We will be using VetRxDirect for a long time.
excellent company to buy from

Rated 5 out of 5 stars
10 years ago
By framy13

From Fairfield, CA, USA

Comments about Trilostane (Compounded)

I searched the Web, and this was the only company that carried the dosage of Trilostane my beagle needs for her cushing's. Ordering is easy, and they contact my vet directly. I have been very happy with their product, and how it continues to help my pet live a longer, happier life.
Great Price Value + Service!!!

Rated 5 out of 5 stars
10 years ago
By The Girls

From Cape Coral, FL, USA

Comments about Trilostane (Compounded)

Vet RX Direct has been compounding a prescription drug for our dog, Mollie, since 2010. We have always found Vet RX Direct to be courteous and prompt. Our dogs always look forward to the box arriving because they know a dog treat will be inside.
Meds have helped my 4-legged son, Jackson!

Rated 5 out of 5 stars
10 years ago
By Puddin puff

From North Carolina, USA

Comments about Trilostane (Compounded)

Jackson (my dog) has a chronic condition that requires this medicine. I'm grateful it has improved his overall health and well-being. We can tell he feels so much better! You would never know his 9 years old-full of energy and overflowing personality.
- Photo 1
Always in stock.

Rated 5 out of 5 stars
10 years ago
By Shan2J

From Tracy, CA, USA

Comments about Trilostane (Compounded)

My dog is reliant on daily medication. VetRx always has his medication in stock
working well

Rated 5 out of 5 stars
10 years ago
By tucker711

From NY, NY

Comments about Trilostane (Compounded)

My dog was put on 10mg of Vetoryl for Cushings and it was not working well for him. He would get very tired and spacey and there was no change in his profuse urination. The 5 mg doses twice a day are making a big difference and I'm very happy we were able to get this dosage compounded.
Trilostane (For treatment of Cushings)

Rated 5 out of 5 stars
11 years ago
By MotherofAPap

From Palm Beach, FL, USA

Comments about Trilostane (Compounded)

My Papillon was diagnosed with Cushings and will be on this medicine for the rest of his life. VetRX service is excellent and this med is effective. Note that this is the generic, saving $.

Displaying Reviews 31 - 40

My dog is currently on 30 twice a day of Vetoryl. What amount of the compounded tablets would he need daily??

Asked by Christina
4 years ago
- Compounded Trilostane is no longer available at our pharmacy. We apologize for the inconvenience.
  
  Holly
  
  Verified Answer
My 30 pound Whippet has been taking 10mg vetoryl 2 times daily. What would be the conversion and dosage if I were to request the trilostane suspension??

Asked by Robin
5 years ago
- The Trilostane (Compounded) suspension is a corn oil based, liquid suspension containing the contents of the Vetoryl Capsules and formulated to the strengths listed on the VetRxDirect home page. As an example, the Trilostane (Compounded) 5mg/ml suspension would require a dose of 2ml twice daily, to be equivalent in dose to a 10mg Vetoryl capsule, twice daily. The oil based Trilostane (Compounded) suspension does not require refrigeration, does require shaking prior to each use and has a beyond-use-date (date at which the product should no longer be used) of 90 days from the date of compounding. Please speak with your veterinarian to determine if a suspension dosage form of trilostane would be appropriate for your dog
  
  VetRxDirect
  
  Verified Answer
If my dog is currently taking 30 mg vetoryl, What would the liquid dosage be if we switched? Trying to compare price if we change?

Asked by melody
5 years ago
- There is a Trilostane 30 mg/mL concentration available, so if your dog is needing 30 mg daily then it would be 1 mL daily with the compounded product. Please check on the VetRxDirect website for current pricing for this product.
  
  VetRxDirect
  
  Verified Answer
How much would it cost to get 180 of Trilostane 6mg capsules??

Asked by Shirley
6 years ago
- Please use the 'Select Product' drop down and 'Enter Quantity' of 360 of the 3mg capsules. Please confirm the exact dose needed for your dog with your veterinarian.
  
  VetRxDirect
  
  Verified Answer
Is it okay to plan on a 0.2mL (i.e. 0.2mL of 50mg/mL for 10mg dose) or will it be too difficult to measure and administer this amount??

Asked by Shane
8 years ago
- This should be difficult to measure as we will give you a syringe with the appropriate markings to measure this amount accurately.
  
  Verified Answer
Is this drug compounded from an FDA approved source such as Vetoryl ? Is the compounded Trilostane FDA approved just like Vetoryl ??

Asked by Les
8 years ago
- Vetoryl is a FDA approved product for the the treatment of hyperadrenocorticism. Compounding trilostane allows for a pharmacist to create a medication that is tailored to the specialized needs of an individual pet according to a veterinarian's prescription. The FDA does recognize that compounding plays an important role in tailoring medications to meet the needs of a patient/pet. Trilostane is compounded by VetRxDirect's expert compounding staff and is available in many dosage forms to tailor to your pet's needs. It would be important to contact your pet's veterinarian to see if compounded trilostane would be a good option for your pet.
  
  Verified Answer
does this product come in liquid form?..........how administered? how do you determine mg dosage? Thanks!?

Asked by Richard
8 years ago
- VetRxDirect offers trilostane in a capsule formulation under the brand name "Vetoryl." It is available in a variety of strengths including 5mg, 10mg, 30mg, and 60mg capsules. In addition, trilostane is also available through VetRxDirect as a compounded capsule formulation. This may be a suitable option for you if your pet's required dose is not commercially available. The medication is administered to the pet by mouth, often in some food or a treat to make it more appealing and palatable. The appropriate strength is dependent upon many factors such as diagnosis, species, concurrent medications, and weight. Please consult your pet's veterinarian to determine which strength would best suit your pet's needs. Thank you, VetRxDirect
  
  Verified Answer
Hi! I was wondering what you used to suspend the trilostane? Is it oil or water-based??

Asked by Erica
8 years ago
- The trilostane suspension is an oil based suspension with silica gel used to suspend the active drug. VetRxDirect places a 90 beyond use date, or the date on which the suspension should no longer be used, after compounding. Thank you, VetRxDirect
  
  Verified Answer
Can the oral suspension of Trilostane cause teeth deterioration? I've noticed since I've been giving my 93# dog the medicine since the end of October, his teeth have gotten quite brown. Gums are red as well. They were pretty white prior.?

Asked by Balloo
10 years ago
- The most common adverse effects seen with trilostane use are lethargy, weakness, loss of appetite for a fews day, vomiting and diarrhea. I am unable to find any medical literature associating teeth or tongue discoloration or deterioration with the use of trilostane. I recommend contacting your veterinarian to determine the cause of this. Thank you, VetRxDirect
  
  VetRxDirect
  
  Community Answer
My 11 year old 54 lb dog has been on a 2 x daily dosage of 0.5 liquid trilostane for 17 days. She is still exhibiting symptoms of Cushings including excessive drinking, urination, panting at rest and increased appetite. How long before she improves??

Asked by Gracie11
10 years ago
- Trilostane is a common treatment for dogs with high cortisol levels or Cushing’s disease. The starting dose of the medication is determined by the weight of the pet and then adjusted according to the cortisol levels and clinical symptoms. Cortisol levels are typically checked 10-14 days after beginning treatment and the dose is then adjusted accordingly. Reaching the optimum dose to control symptoms and reduce side effects may take several dose adjustments. It is important to follow up with all appointments. It may be beneficial to contact your veterinarian and report your dogs continued clinical symptoms after 17 days of treatment. Thank you, VetRxDirect
  
  VetRxDirect
  
  Community Answer

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