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S-Adenosyl is currently unavailable. Please check back with us at another time as we are uncertain when we will have more in stock.


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Many people use the supplement S-Adenosyl, commonly known as SAMe, and swear by the results. Now pets can benefit form this natural supplement too. SAMe is a detoxifier and antioxidant with many properties that help dogs and cats.

  •  Supports healthy liver function
  •  Relieves pain and swelling due to osteoarthritis
  •  Improves cognitive function
  •  Snap Tabs variation provides four equal parts for a wide range of weights.

SAMe is best known for improving liver function and metabolic activity in dogs and cats. But this powerful supplement containing milk thistle does much more. SAMe helps treat cognitive disorders, depression, and hepatitis. It’s also effective in treating osteoarthritis by reducing inflammation and helping to regenerate joint tissue.


What you should know about S-Adenosyl:

  •  Talk to your veterinarian before using this product.
  •  Follow dosing directions exactly - don’t give your pet more medication than directed and don’t skip doses.
  •  Read the label carefully for information about storage, possible side effects, and drug interactions.


For additional information about S-Adenosyl, click the “More Information” and “Package Insert” tabs above. 

You can find a Client Information Sheet which provides a summary of information about S-Adenosyl by following the link below:

SAMe Client Information Sheet*


If you have questions or concerns about S-Adenosylmethionine, or conditions related to its use, contact your pet's veterinarian or pharmacist.


*This link opens in a new window.

You can find a package label which provides more detailed information on S-Adenosyl's indications, forms of administration, and side effects, along with other clinical information, by following the link below:

S-Adenosyl 100 Package Label*

S-Adenosyl 225 Package Label*

S-Adenosyl 425 Package Label


S-Adenosyl's package insert does not take the place of instructions from your veterinarian. Talk to your pet’s veterinarian or pharmacist if you do not understand the information provided in this document or if you have any questions about S-Adenosyl SAMe made with milk thistle for dogs.


*This link opens in a new window.