Trifexis Rx

  • Usually ships within one business day with veterinary approval.

  • Requires veterinary authorization.

  • Your pet's veterinarian will provide directions for use.


Trifexis is a triple acting parasite prevention treatment for dogs. Trifexis is a prescription heartworm disease preventative that contains spinosad, an insecticide and milbemycin oxime, a parasiticide. It starts killing fleas within 30 minutes, prevents re-infestation, and prevents the tapeworms they carry. Trifexis also treats and controls the infection of 3 intestinal parasites: roundworms, whipworms, and hookworms. It provides 1 month of protection and is a flavored chewable tablet, making it easier to give  Trifexis is for use in dogs and puppies 8 weeks of age or older and 5 pounds of body weight or greater. Available in six sizes based on weight: 5-10 lbs, 10.1-20 lbs, 20.1-40 lbs, 40.1-60 lbs, 60.1-120 lbs.

  • Read and follow the prescription label carefully for storage information, possible side effects, and drug interactions.
  • Give the exact amount prescribed and only as often as directed.
  • Do not skip doses or stop giving the medication without consulting your veterinarian.