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Simparica Trio is a monthly chewable for dogs that prevents heartworm disease, treats intestinal parasite infection, and kills fleas and ticks. Simparica Trio contains three active ingredients: sarolaner, moxidectin, and pyrantel for triple protection from parasites. Simparica Trio prevents heartworm disease in dogs, as well as treats and controls roundworm and hookworm infections. It kills 5 species of ticks including the gulf coast tick, american dog tick, lone star tick, deer tick, and brown dog tick. Simparica Trio starts killing fleas within 4 hours and kills fleas before they can lay eggs. This highly palatable, liver-flavored chewable tablet provides 1 month of protection. For dogs and puppies 8 weeks of age or older weighing 2.8 lbs or more. Simparica Trio is available in six sizes for dogs packaged in 6 month supply.