Proin (Phenylpropanolamine) Rx
Proin (Phenylpropanolamine) Rx
Due to updated controlled substance requirements, we no longer carry Proin. Please see the end of our Urinary Incontinence in Dogs blog post for an important message about Proin and VetRxDirect.
Proin
When your dog is incontinent it’s uncomfortable for your pet and a messy problem for you. Talk to your veterinarian about Proin, a prescription medication for treating urinary incontinence. Proin reduces leakage by tightening the bladder sphincter muscle.
- Manages urinary incontinence in dogs
- Tightens the bladder sphincter muscle to control urine leakage
- Choose easy dosing liquid or chewable tablets
Age, disease, urinary stones, and even injury can cause a dog to loose complete control over her bladder. When that happens even a housetrained pet may dribble urine or loose large amounts of urine suddenly. If your dog has urinary incontinence, prescription Proin may help. The active ingredient in Proin, phenylpropanolamine, is a type of stimulant that causes the muscles in the bladder to contract therefore reducing urine leakage. Given over time, Proin keeps a constant level of phenylpropanolamine in the blood so your dog will have more bladder control. Note: Proin is classified as a controlled substance in our home state of Iowa, so prescriptions for Proin are only valid for six months. We must obtain a new prescription from your veterinarian every six months. Refill requests that exceed six months from the prescription date are not valid for this medication.
What you should know about Proin:
- Talk to your veterinarian before using this product.
- Follow dosing directions exactly - don’t give your pet more medication than directed and don’t skip doses.
- Read the label carefully for information about storage, possible side effects, and drug interactions.
For additional information about Proin, click the “More Information” and “Package Insert” tabs above.
Review Summary
14 total reviews
Rated 4.71 out of 5 stars
0% of respondents would recommend this to a friend
Ratings Distribution
10 5 star reviews
4 4 star reviews
0 3 star reviews
0 2 star reviews
0 1 star reviews
Reviews
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This is the first renewal of the Proin tablets. I had the...
From UndisclosedComments about Proin (Phenylpropanolamine)This is the first renewal of the Proin tablets. I had the liquid before and it worked so much better for my dog. She doesn't like to take pills. But the liquid was not available. The service was good. -
Quick & Easy
From Golden Valley, AZ, USAComments about Proin (Phenylpropanolamine)I have been purchasing this product from Vet Rx Direct for over a year. This time my vet would not fill the script without seeing my Dutchess even though she had refills available. Vet Rx Direct contacted me right away with the problem but held my order and did not cancel it. The next day Dutchess saw her vet and within two days her medication was on my doorstep. She loves the special cookies and the personalized cards that they send so we feel as if we know the wonderful person who took care of the order. -
proin offers relief to aging dog and owners
From Edmonds, WA, USAComments about Proin (Phenylpropanolamine)Works most of the time. It offers relief and embarrassment our 14 year old husky. Stops that sudden unexplained wetting which is hard on all of us. -
Easy to take
From State College, PA, USAComments about Proin (Phenylpropanolamine)I have been giving this to my dog to help with bladder control issues. Works very well and the dog takes it easily. -
A Necessary Evil
From Anchorage AlaskaComments about Proin (Phenylpropanolamine)Unfortunately, my lil girl has to be on this med for the rest of her life. The initial prescribed dose, which worked fine for 6 months, had to be increased when she had breakthrough urination. -
Excellent service!
From Berkeley, CA, USAComments about Proin (Phenylpropanolamine)This is the second time I've bought this product for my German Shepard and I'm really happy with the service. I appreciate that VetRxDirect contacted my vet to renew the prescription and shipped the package within a few days of when I placed the order. And the price was much lower than what I paid at our vet. I will definitely continue to use VetRxDirect for our dog's prescription needs.-
![Excellent service!]()
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Controls his incontinence!
From Winthrop, ME, USAComments about Proin (Phenylpropanolamine)Our 9 yr. old Chesapeake Bay Retriever has had incontinence issues for 5 years. We were able to control it with ProIn, initially at a lower dose. As he has gotten older the dose has had to be increased. We had also used this with a previous older female dog who developed incontinence. We use it under the supervision of our vet. -
great product and great customer service that really care
From Miami, FL, USAComments about Proin (Phenylpropanolamine)great product and great customer service that really care -
Effective with no discernible side effects
From Pomona, CA, USAComments about Proin (Phenylpropanolamine)I have reduced the amount of Proin from one tablet at night, a half-tablet in the morning and my 10-year-old German Shepherd mix has not leaked. �I would like to reduce dosage further, but but don't want to take the risk of leakage. -
Great Service
From McCleary, WA, USAComments about Proin (Phenylpropanolamine)One of dogs has to take proin twice a day. It is nice to be able to order her meds ahead online so I always have a constant supply. Much cheaper than at the vet is an added bonus.
Displaying Reviews 1 - 10
Q & A
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I have an extremely hard time giving this pill (and any pill) to my dog. She will not chew these + she can regurgitate pills at will. Can I crush these up + mix with a tiny amount of liquid + give via oral syringe without disrupting the medicinal value? ?
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Proin does have a bitter taste for dogs. It is best to give the chewable tablets with food to mask the taste. If this hasn’t worked for you, when speaking with the manufacturer, it is NOT recommended to crush and give via oral syringe. We would suggest you contact your veterinarian for further options on treatment. Thank you, VetRxDirect
Community Answer
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do I need a prescription to purchase Proin??
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Ronda, Yes, Proin is a prescription medication. It is also considered a controlled substance, so it is not available to ship to every state, depending on the state controlled substance laws. If it is available to ship to your state, then we can accept the prescription from your dog's veterinarian in a couple of different ways. Once you have placed your order, we can send a fax directly to the veterinary clinic you list which the clinic may then fax back, or, the clinic may choose to issue you a written prescription which you can then mail to us. Once we receive the prescription, we will process and ship out your order. Thank you, VetRxDirect
Community Answer
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My lab does not like the taste of the chewables and spits them out, even when hidden with his regular kibble. Is there a pill form or another option to try??
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Unfortunately, the liquid phenylpropanolamine (Proin drops) were discontinued by the manufacturer and we are not currently aware of any other dosage form available for this medication. If you are concerned about your pet obtaining a regular dose of the Proin, or you worry that the medication is not working, you should contact your lab's veterinarian about alternative treatments; if you're unable to administer the Proin regularly or effectively, there may be another treatment that would be easier and more effective for you and your lab. Thank you, VetRxDirect
Community Answer
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Our dog is on prion are these chewable??
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Yes, and mine loves it!
Community Answer
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Is it okay to give this drug when the dog has a full stomach or does it have to be given on an empty stomach for best results? Thank you.?
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Barb, This drug can be given without regard to meals, however it is important to give the medicine at a consistent time each day. Thank you, VetRxDirect
Community Answer
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where online would I get Proin liquid medication???
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Alicia, We no longer carry the Proin drops as they have been discontinued by the manufacturer and are no longer available. You should talk to your dog's veterinarian about alternative treatment options. Thank you, VetRxDirect
Community Answer
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I do not see what the dosage is for a dog that is 20 lbs. Is this a medication that needs to be taken for the life of the dog to prevent incontinence or will the bladder correct itself and able to stop taking the medication??
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Sonja, Proin (phenylpropanolamine) is used to treat incontinence in dogs. Incontinence may present in different ways but typically requires medication to be given long-term. One reference recommends a dosing range of phenylpropanolamine immediate release - 9mg to 18mg two to three times daily for a 20lb dog. Your veterinarian will determine a more accurate dosing regimen based on the reason for your dog’s incontinence. Thank you, VetRxDirect
Community Answer
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Are they no longer making proin drops? My dog was taking them but now I have to try to get the pill form into him.?
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You shouldn't have to "get it into him". The tablets are flavored chewable. My dog begs for them, lol
Community Answer -
Cathy, Proin drops have been discontinued by the manufacturer. The only form in which Proin is currently available is tablet form. Thank you, VetRxDirect
Community Answer
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Can I buy this product from Brazil with a brazilian prescription ?tks?
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Mateus, Sorry, VetRxDirect does not ship outside of the U.S. Thank you, VetRxDirect
Community Answer
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How does this medication work? I understand what the medication is for, but don't know how it really works. Why can't I just stop this medication? What will happen to my dog??
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Patricia, Proin works mainly by constricting a type of muscle called smooth muscle in your dog's blood vessels and the muscle of the urethra. The effect seen is increased blood pressure and increased tone of the urethral muscle to help with problems such as congestion or incontinence. If the medication is stopped abruptly, events such as low blood pressure might occur and lead to things like dizziness or recurrence of incontinence symptoms. Contact your veterinarian before discontinuing your dog's medication. Thank you, VetRxDirect
Community Answer
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Displaying Questions 1 - 10