ADVAIR treats both main causes of asthma symptoms—airway constriction and inflammation—to help prevent symptoms in the first place.
What is ADVAIR HFA?
ADVAIR HFA combines an inhaled corticosteroid medicine, fluticasone propionate (the same
medicine found in FLOVENT) and a long-acting
medicine found in SEREVENT). ADVAIR HFA is used for asthma as follows:
ADVAIR HFA is used long term, to control symptoms of asthma, and prevent symptoms such as wheezing.
To help administer Advair, we recommend the use of either an AeroKat Feline Aerosol Chamber or an AeroDawg Canine Aerosol Chamber.
MEDICATION GUIDE
ADVAIR® HFA [adv
(fluticasone propionate 45 mcg and salmeterol 21 mcg)
ADVAIR® HFA 115/21 Inhalation Aerosol
(fluticasone propionate 115 mcg and salmeterol 21 mcg)
ADVAIR® HFA 230/21 Inhalation Aerosol
(fluticasone propionate 230 mcg and salmeterol 21 mcg)
air] 45/21 Inhalation AerosolRead the Medication Guide that comes with ADVAIR HFA before you start using it and each
time you get a refill. There may be new information. This Medication Guide does not take the
place of talking to your healthcare provider about your medical condition or treatment.
What is the most important information I should know about ADVAIR HFA?
•
ADVAIR HFA contains 2 medicines:
•
, an inhaled
corticosteroid medicine. Inhaled corticosteroids help to decrease inflammation in the
lungs. Inflammation in the lungs can lead to asthma symptoms.
•
-agonist
medicine or LABA. LABA medicines are used in patients with asthma. LABA medicines
help the muscles around the airways in your lungs stay relaxed to prevent symptoms,
such as wheezing and shortness of breath. These symptoms can happen when the muscles
around the airways tighten. This makes it hard to breathe. In severe cases, wheezing can
stop your breathing and cause death if not treated right away.
•
In patients with asthma, LABA medicines, such as salmeterol (one of the medicines in
ADVAIR HFA), may increase the chance of death from asthma problems.
In a large
asthma study, more patients who used salmeterol died from asthma problems compared with
patients who did not use salmeterol. It is not known whether fluticasone propionate, the other
medicine in ADVAIR HFA, changes your chance of death from asthma problems seen with
salmeterol. Talk with your healthcare provider about this risk and the benefits of treating
your asthma with ADVAIR HFA.
MEDICATION GUIDE
ADVAIR® HFA [adv
(fluticasone propionate 45 mcg and salmeterol 21 mcg)
ADVAIR® HFA 115/21 Inhalation Aerosol
(fluticasone propionate 115 mcg and salmeterol 21 mcg)
ADVAIR® HFA 230/21 Inhalation Aerosol
(fluticasone propionate 230 mcg and salmeterol 21 mcg)
air] 45/21 Inhalation AerosolRead the Medication Guide that comes with ADVAIR HFA before you start using it and each
time you get a refill. There may be new information. This Medication Guide does not take the
place of talking to your healthcare provider about your medical condition or treatment.
What is the most important information I should know about ADVAIR HFA?
•
ADVAIR HFA contains 2 medicines:
•
, an inhaled
corticosteroid medicine. Inhaled corticosteroids help to decrease inflammation in the
lungs. Inflammation in the lungs can lead to asthma symptoms.
•
-agonist
medicine or LABA. LABA medicines are used in patients with asthma. LABA medicines
help the muscles around the airways in your lungs stay relaxed to prevent symptoms,
such as wheezing and shortness of breath. These symptoms can happen when the muscles
around the airways tighten. This makes it hard to breathe. In severe cases, wheezing can
stop your breathing and cause death if not treated right away.
•
In patients with asthma, LABA medicines, such as salmeterol (one of the medicines in
ADVAIR HFA), may increase the chance of death from asthma problems.
In a large
asthma study, more patients who used salmeterol died from asthma problems compared with
patients who did not use salmeterol. It is not known whether fluticasone propionate, the other
medicine in ADVAIR HFA, changes your chance of death from asthma problems seen with
salmeterol. Talk with your healthcare provider about this risk and the benefits of treating
your asthma with ADVAIR HFA.
•
ADVAIR HFA does not relieve sudden symptoms. Always have a short-acting
beta
•
Do not stop using ADVAIR HFA unless told to do so by your healthcare provider
because your symptoms might get worse.
•
ADVAIR HFA should be used only if your healthcare provider decides that another
asthma-controller medicine alone does not control your asthma or that you need 2
asthma-controller medicines.
•
Call your healthcare provider if breathing problems worsen over time while using
ADVAIR HFA. You may need different treatment.
•
Get emergency medical care if:
•
breathing problems worsen quickly, and
•
you use your short-acting beta2-agonist medicine, but it does not relieve your
breathing problems.
What is ADVAIR HFA?
ADVAIR HFA combines an inhaled corticosteroid medicine, fluticasone propionate (the same
medicine found in FLOVENT) and a long
agonist medicine, salmeterol (the same
medicine found in SEREVENT). ADVAIR HFA is used for asthma as follows:
ADVAIR HFA is used long term, twice a day to control symptoms of asthma, and prevent
symptoms such as wheezing in adolescents and adults 12 years of age and older.
ADVAIR HFA contains salmeterol (the same medicine found in SEREVENT). Because
LABA medicines, such as salmeterol, may increase the chance of death from asthma
problems, ADVAIR HFA is not for adults and children with asthma who:
are well controlled with another asthma-controller medicine, such as a low to medium
dose of an inhaled corticosteroid medicine
•
-agonist medicines once in awhile
What should I tell my healthcare provider before using ADVAIR HFA?
Tell your healthcare provider about all of your health conditions, including if you:
•
have heart problems
•
have high blood pressure
•
have seizures
•
have thyroid problems
•
have diabetes
•
have liver problems
•
have osteoporosis
•
have an immune system problem
•
It is not known if ADVAIR HFA may harm
your unborn baby.
•
It is not known if ADVAIR HFA passes into your milk and if it can harm
your baby.
•
are allergic to ADVAIR HFA or any other medicines
•
are exposed to chickenpox or measles
Tell your healthcare provider about all the medicines you take including prescription and
non-prescription medicines, vitamins, and herbal supplements. ADVAIR HFA and certain other
medicines may interact with each other. This may cause serious side effects. Especially, tell your
healthcare provider if you take ritonavir. The anti-HIV medicines NORVIR
(ritonavir capsules)
Soft Gelatin, NORVIR (ritonavir oral solution), and KALETRA
(lopinavir/ritonavir) Tablets
contain ritonavir.
Know the medicines you take. Keep a list and show it to your healthcare provider and pharmacist
each time you get a new medicine.
How do I use ADVAIR HFA?
See the step-by-step instructions for using ADVAIR HFA at the end of this Medication
Guide.
Do not use the ADVAIR HFA unless your healthcare provider has taught you and you
understand everything. Ask your healthcare provider or pharmacist if you have any questions.
•
Use ADVAIR HFA exactly as prescribed.
Do not use ADVAIR HFA more often than
prescribed.
ADVAIR HFA comes in 3 strengths. Your healthcare provider will prescribe the
one that is best for your condition.
•
The usual dosage of ADVAIR HFA is 2 inhalations twice a day (morning and evening). The
2 doses should be about 12 hours apart. Rinse your mouth with water after using ADVAIR
HFA.
•
If you miss a dose of ADVAIR HFA, just skip that dose. Take your next dose at your usual
time. Do not take 2 doses at one time.
•
While you are using ADVAIR HFA twice a day, do not use other medicines that contain
a long-acting beta
•
Do not change or stop any of your medicines used to control or treat your breathing
problems. Your healthcare provider will adjust your medicines as needed.
•
Make sure you always have a short-acting beta2
-agonist medicine with you. Use your
short-acting beta
2
-agonist medicine if you have breathing problems between doses of
ADVAIR HFA.
•
Call your healthcare provider or get medical care right away if:
•
your breathing problems worsen with ADVAIR HFA
•
you need to use your short-acting beta2
-agonist medicine more often than usual
•
your short-acting beta2
-agonist medicine does not work as well for you at relieving
symptoms
•
you need to use 4 or more inhalations of your short-acting beta2
-agonist medicine for 2 or
more days in a row
•
you use 1 whole canister of your short-acting beta2
-agonist medicine in 8 weeks’ time
•
your peak flow meter results decrease. Your healthcare provider will tell you the numbers
that are right for you.
•
you have asthma and your symptoms do not improve after using ADVAIR HFA regularly
for 1 week
What are the possible side effects with ADVAIR HFA?
•
ADVAIR HFA contains salmeterol (the same medicine found in SEREVENT). In
patients with asthma, LABA medicines, such as salmeterol, may increase the chance of
death from asthma problems.
See “What is the most important information I should know
about ADVAIR HFA?”
Other possible side effects with ADVAIR HFA include:
•
serious allergic reactions including rash; hives; swelling of the face, mouth, and tongue;
and breathing problems.
Call your healthcare provider or get emergency medical care if
you get any symptoms of a serious allergic reaction.
•
increased blood pressure
•
a fast and irregular heartbeat
•
chest pain
•
headache
•
tremor
•
nervousness
•
immune system effects and a higher chance for infections
•
lower bone mineral density.
This may be a problem for people who already have a higher
chance for low bone density (osteoporosis).
•
eye problems including glaucoma and cataracts.
You should have regular eye exams
while using ADVAIR HFA.
•
slowed growth in children.
A child’s growth should be checked often.
•
throat irritation
Tell your healthcare provider about any side effect that bothers you or that does not go away.
These are not all the side effects with ADVAIR HFA. Ask your healthcare provider or
pharmacist for more information.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-
800-FDA-1088.
How do I store ADVAIR HFA?
•
Store ADVAIR HFA at room temperature with the mouthpiece down.
•
Do not puncture the canister. Do not use or store ADVAIR HFA near heat or an open
flame. Never throw it into a fire or incinerator.
•
Keep ADVAIR HFA and all medicines out of the reach of children.
General Information about ADVAIR HFA
Medicines are sometimes prescribed for purposes not mentioned in a Medication Guide. Do not
use ADVAIR HFA for a condition for which it was not prescribed. Do not give your ADVAIR
HFA to other people, even if they have the same condition. It may harm them.
This Medication Guide summarizes the most important information about ADVAIR HFA. If you
would like more information, talk with your healthcare provider or pharmacist. You can ask your
healthcare provider or pharmacist for information about ADVAIR HFA that was written for
healthcare professionals. You can also contact the company that makes ADVAIR HFA (toll free)
at 1-888-825-5249 or at www.advair.com.
Instructions for Using Your ADVAIR HFA
Follow the instructions below for using your ADVAIR HFA.
Take your ADVAIR HFA inhaler out of the moisture-protective foil pouch just before you use it
for the first time. Safely throw away the foil pouch and the drying packet that comes inside the
pouch.
The inhaler should be at room temperature before you use it.
The purple actuator that comes with ADVAIR HFA should not be used with any other
product canisters. Actuators that come with other products should not be used with an
ADVAIR HFA canister.
Prime the inhaler
before using it for the first time. To prime the inhaler, shake it well for
5 seconds. Then spray it 1 time into the air away from your face. Shake and spray the inhaler like
this 3 more times to finish priming it.
Avoid spraying in eyes.
If you have not used your inhaler in more than 4 weeks or if you have dropped it, shake it well
for 5 seconds and spray it 2 times into the air away from your face.
Shake the inhaler well
for 5 seconds just before each use.1.
Take the cap off the mouthpiece (see Figure 1). The strap on the cap will stay attached to the
actuator.
Look for foreign objects inside the inhaler before each use, especially if the strap is no longer
attached to the actuator or if the cap is not being used to cover the mouthpiece.
Make sure the canister is fully and firmly inserted into the actuator.
Shake the inhaler well
for 5 seconds right before each use.
Figure 1
2. Breathe out fully through your mouth,
pushing as much air out of your lungs as you can.
Put the mouthpiece all the way into your mouth. Hold the inhaler with the mouthpiece down
(see Figure 1). Close your lips around it.
3.
It is important to get the medicine in the spray into your lungs where it works. To do this, you
need to
inhale the spray at the same time you take in a slow, deep breath
.
So, just after starting to take in a slow, deep breath through your mouth, press down firmly on
the top of the metal canister (see Figure 2) and keep breathing in through your mouth.
Take your finger off the canister after the spray comes out of the canister. Take the
mouthpiece out of your mouth after you have finished breathing in.
Figure 2
4.
Hold your breath as long as you can
, up to 10 seconds. Then breathe normally.
5.
Wait about 30 seconds and shake
the inhaler again. Repeat steps 2 through 4.
6.
Put the cap back on the mouthpiece after each time you use the inhaler.
7. After you finish taking this medicine, rinse your mouth with water. Spit out the water. Do not
swallow it.
8. Never put the canister in water to find out how much medicine is left in the canister (“float
test”).
9. You should keep track of the number of inhalations used from your inhaler.
Then throw away
the inhaler after you have used 120 inhalations.
Even though the canister might not be empty
and will keep spraying, you might not get the right amount of medicine in each inhalation.
Before you get to 120 inhalations, ask your doctor if you need to refill your prescription.
Do not
use after the expiration date, which is shown as “EXP” on the product label and box.Cleaning your ADVAIR HFA Inhalation Aerosol:
Clean the inhaler at least once a week after your evening dose. Keeping the canister and plastic
actuator clean is important to prevent medicine buildup.
Step 1. Take the cap off the mouthpiece. The strap on the cap will stay attached to the actuator.
Do not take the canister out of the plastic actuator.
Step 2. Use a dry cotton swab to clean the small circular opening where the medicine sprays out
of the canister. Carefully twist the swab in a circular motion to take off any medicine (see Figure
3). Then wipe the inside of the mouthpiece with a clean tissue dampened with water. Let the
actuator air-dry overnight.
Figure 3
Step 3. Put the mouthpiece cover back on after the actuator has dried.
Rx only
GlaxoSmithKline
Research Triangle Park, NC 27709
ADVAIR, ADVAIR DISKUS, FLOVENT, SEREVENT, and DISKUS are registered trademarks
of GlaxoSmithKline.
The following are registered trademarks of their respective manufacturers: NORVIR and
KALETRA/Abbott Laboratories, FORADIL AEROLIZER/Novartis Pharmaceuticals
Corporation, SYMBICORT/AstraZeneca group of companies. The following are trademarks of
their respective manufacturers: PERFOROMIST/Dey, L.P.; BROVANA/Sepracor Inc.
©Year, GlaxoSmithKline. All rights reserved.
Month Year
This Medication Guide has been approved by the U.S. Food and Drug Administration.
2-agonist or LABA for any reason. Other LABA-containing medicines
include ADVAIR DISKUS
® (fluticasone propionate and salmeterol inhalation powder),
SEREVENT
® DISKUS® (salmeterol xinafoate inhalation powder), FORADIL®
AEROLIZER
® (formoterol fumarate inhalation powder), SYMBICORT® (budesonide
and formoterol fumarate dihydrate) Inhalation Aerosol, PERFOROMIST™
(formoterol fumarate) Inhalation Solution, and BROVANA™ (arformoterol tartrate)
Inhalation Solution.
2-agonist medicine with you to treat sudden symptoms. If you do not have an
inhaled, short-acting bronchodilator, contact your healthcare provider to have one
prescribed for you.
ADVAIR® HFA [adv
(fluticasone propionate 45 mcg and salmeterol 21 mcg)
ADVAIR® HFA 115/21 Inhalation Aerosol
(fluticasone propionate 115 mcg and salmeterol 21 mcg)
ADVAIR® HFA 230/21 Inhalation Aerosol
(fluticasone propionate 230 mcg and salmeterol 21 mcg)
•
ADVAIR HFA does not relieve sudden symptoms. Always have a short-acting
beta
•
Do not stop using ADVAIR HFA unless told to do so by your healthcare provider
because your symptoms might get worse.
•
ADVAIR HFA should be used only if your healthcare provider decides that another
asthma-controller medicine alone does not control your asthma or that you need 2
asthma-controller medicines.
•
Call your healthcare provider if breathing problems worsen over time while using
ADVAIR HFA. You may need different treatment.
•
Get emergency medical care if:
•
breathing problems worsen quickly, and
•
you use your short-acting beta2-agonist medicine, but it does not relieve your
breathing problems.
What is ADVAIR HFA?
ADVAIR HFA combines an inhaled corticosteroid medicine, fluticasone propionate (the same
medicine found in FLOVENT) and a long
agonist medicine, salmeterol (the same
medicine found in SEREVENT). ADVAIR HFA is used for asthma as follows:
ADVAIR HFA is used long term, twice a day to control symptoms of asthma, and prevent
symptoms such as wheezing in adolescents and adults 12 years of age and older.
ADVAIR HFA contains salmeterol (the same medicine found in SEREVENT). Because
LABA medicines, such as salmeterol, may increase the chance of death from asthma
problems, ADVAIR HFA is not for adults and children with asthma who:
are well controlled with another asthma-controller medicine, such as a low to medium
dose of an inhaled corticosteroid medicine
•
-agonist medicines once in awhile
What should I tell my healthcare provider before using ADVAIR HFA?
Tell your healthcare provider about all of your health conditions, including if you:
•
have heart problems
•
have high blood pressure
•
have seizures
•
have thyroid problems
•
have diabetes
•
have liver problems
•
have osteoporosis
•
have an immune system problem
•
It is not known if ADVAIR HFA may harm
your unborn baby.
•
It is not known if ADVAIR HFA passes into your milk and if it can harm
your baby.
•
are allergic to ADVAIR HFA or any other medicines
•
are exposed to chickenpox or measles
Tell your healthcare provider about all the medicines you take including prescription and
non-prescription medicines, vitamins, and herbal supplements. ADVAIR HFA and certain other
medicines may interact with each other. This may cause serious side effects. Especially, tell your
healthcare provider if you take ritonavir. The anti-HIV medicines NORVIR
(ritonavir capsules)
Soft Gelatin, NORVIR (ritonavir oral solution), and KALETRA
(lopinavir/ritonavir) Tablets
contain ritonavir.
Know the medicines you take. Keep a list and show it to your healthcare provider and pharmacist
each time you get a new medicine.
How do I use ADVAIR HFA?
See the step-by-step instructions for using ADVAIR HFA at the end of this Medication
Guide.
Do not use the ADVAIR HFA unless your healthcare provider has taught you and you
understand everything. Ask your healthcare provider or pharmacist if you have any questions.
•
Use ADVAIR HFA exactly as prescribed.
Do not use ADVAIR HFA more often than
prescribed.
ADVAIR HFA comes in 3 strengths. Your healthcare provider will prescribe the
one that is best for your condition.
•
The usual dosage of ADVAIR HFA is 2 inhalations twice a day (morning and evening). The
2 doses should be about 12 hours apart. Rinse your mouth with water after using ADVAIR
HFA.
•
If you miss a dose of ADVAIR HFA, just skip that dose. Take your next dose at your usual
time. Do not take 2 doses at one time.
•
While you are using ADVAIR HFA twice a day, do not use other medicines that contain
a long-acting beta
•
Do not change or stop any of your medicines used to control or treat your breathing
problems. Your healthcare provider will adjust your medicines as needed.
•
Make sure you always have a short-acting beta2
-agonist medicine with you. Use your
short-acting beta
2
-agonist medicine if you have breathing problems between doses of
ADVAIR HFA.
•
Call your healthcare provider or get medical care right away if:
•
your breathing problems worsen with ADVAIR HFA
•
you need to use your short-acting beta2
-agonist medicine more often than usual
•
your short-acting beta2
-agonist medicine does not work as well for you at relieving
symptoms
•
you need to use 4 or more inhalations of your short-acting beta2
-agonist medicine for 2 or
more days in a row
•
you use 1 whole canister of your short-acting beta2
-agonist medicine in 8 weeks’ time
•
your peak flow meter results decrease. Your healthcare provider will tell you the numbers
that are right for you.
•
you have asthma and your symptoms do not improve after using ADVAIR HFA regularly
for 1 week
What are the possible side effects with ADVAIR HFA?
•
ADVAIR HFA contains salmeterol (the same medicine found in SEREVENT). In
patients with asthma, LABA medicines, such as salmeterol, may increase the chance of
death from asthma problems.
See “What is the most important information I should know
about ADVAIR HFA?”
Other possible side effects with ADVAIR HFA include:
•
serious allergic reactions including rash; hives; swelling of the face, mouth, and tongue;
and breathing problems.
Call your healthcare provider or get emergency medical care if
you get any symptoms of a serious allergic reaction.
•
increased blood pressure
•
a fast and irregular heartbeat
•
chest pain
•
headache
•
tremor
•
nervousness
•
immune system effects and a higher chance for infections
•
lower bone mineral density.
This may be a problem for people who already have a higher
chance for low bone density (osteoporosis).
•
eye problems including glaucoma and cataracts.
You should have regular eye exams
while using ADVAIR HFA.
•
slowed growth in children.
A child’s growth should be checked often.
•
throat irritation
Tell your healthcare provider about any side effect that bothers you or that does not go away.
These are not all the side effects with ADVAIR HFA. Ask your healthcare provider or
pharmacist for more information.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-
800-FDA-1088.
How do I store ADVAIR HFA?
•
Store ADVAIR HFA at room temperature with the mouthpiece down.
•
Do not puncture the canister. Do not use or store ADVAIR HFA near heat or an open
flame. Never throw it into a fire or incinerator.
•
Keep ADVAIR HFA and all medicines out of the reach of children.
General Information about ADVAIR HFA
Medicines are sometimes prescribed for purposes not mentioned in a Medication Guide. Do not
use ADVAIR HFA for a condition for which it was not prescribed. Do not give your ADVAIR
HFA to other people, even if they have the same condition. It may harm them.
This Medication Guide summarizes the most important information about ADVAIR HFA. If you
would like more information, talk with your healthcare provider or pharmacist. You can ask your
healthcare provider or pharmacist for information about ADVAIR HFA that was written for
healthcare professionals. You can also contact the company that makes ADVAIR HFA (toll free)
at 1-888-825-5249 or at www.advair.com.
Instructions for Using Your ADVAIR HFA
Follow the instructions below for using your ADVAIR HFA.
Take your ADVAIR HFA inhaler out of the moisture-protective foil pouch just before you use it
for the first time. Safely throw away the foil pouch and the drying packet that comes inside the
pouch.
The inhaler should be at room temperature before you use it.
The purple actuator that comes with ADVAIR HFA should not be used with any other
product canisters. Actuators that come with other products should not be used with an
ADVAIR HFA canister.
Prime the inhaler
before using it for the first time. To prime the inhaler, shake it well for
5 seconds. Then spray it 1 time into the air away from your face. Shake and spray the inhaler like
this 3 more times to finish priming it.
Avoid spraying in eyes.
If you have not used your inhaler in more than 4 weeks or if you have dropped it, shake it well
for 5 seconds and spray it 2 times into the air away from your face.
Shake the inhaler well
for 5 seconds just before each use.1.
Take the cap off the mouthpiece (see Figure 1). The strap on the cap will stay attached to the
actuator.
Look for foreign objects inside the inhaler before each use, especially if the strap is no longer
attached to the actuator or if the cap is not being used to cover the mouthpiece.
Make sure the canister is fully and firmly inserted into the actuator.
Shake the inhaler well
for 5 seconds right before each use.
Figure 1
2. Breathe out fully through your mouth,
pushing as much air out of your lungs as you can.
Put the mouthpiece all the way into your mouth. Hold the inhaler with the mouthpiece down
(see Figure 1). Close your lips around it.
3.
It is important to get the medicine in the spray into your lungs where it works. To do this, you
need to
inhale the spray at the same time you take in a slow, deep breath
.
So, just after starting to take in a slow, deep breath through your mouth, press down firmly on
the top of the metal canister (see Figure 2) and keep breathing in through your mouth.
Take your finger off the canister after the spray comes out of the canister. Take the
mouthpiece out of your mouth after you have finished breathing in.
Figure 2
4.
Hold your breath as long as you can
, up to 10 seconds. Then breathe normally.
5.
Wait about 30 seconds and shake
the inhaler again. Repeat steps 2 through 4.
6.
Put the cap back on the mouthpiece after each time you use the inhaler.
7. After you finish taking this medicine, rinse your mouth with water. Spit out the water. Do not
swallow it.
8. Never put the canister in water to find out how much medicine is left in the canister (“float
test”).
9. You should keep track of the number of inhalations used from your inhaler.
Then throw away
the inhaler after you have used 120 inhalations.
Even though the canister might not be empty
and will keep spraying, you might not get the right amount of medicine in each inhalation.
Before you get to 120 inhalations, ask your doctor if you need to refill your prescription.
Do not
use after the expiration date, which is shown as “EXP” on the product label and box.Cleaning your ADVAIR HFA Inhalation Aerosol:
Clean the inhaler at least once a week after your evening dose. Keeping the canister and plastic
actuator clean is important to prevent medicine buildup.
Step 1. Take the cap off the mouthpiece. The strap on the cap will stay attached to the actuator.
Do not take the canister out of the plastic actuator.
Step 2. Use a dry cotton swab to clean the small circular opening where the medicine sprays out
of the canister. Carefully twist the swab in a circular motion to take off any medicine (see Figure
3). Then wipe the inside of the mouthpiece with a clean tissue dampened with water. Let the
actuator air-dry overnight.
Figure 3
Step 3. Put the mouthpiece cover back on after the actuator has dried.
Rx only
GlaxoSmithKline
Research Triangle Park, NC 27709
ADVAIR, ADVAIR DISKUS, FLOVENT, SEREVENT, and DISKUS are registered trademarks
of GlaxoSmithKline.
The following are registered trademarks of their respective manufacturers: NORVIR and
KALETRA/Abbott Laboratories, FORADIL AEROLIZER/Novartis Pharmaceuticals
Corporation, SYMBICORT/AstraZeneca group of companies. The following are trademarks of
their respective manufacturers: PERFOROMIST/Dey, L.P.; BROVANA/Sepracor Inc.
©Year, GlaxoSmithKline. All rights reserved.
Month Year
This Medication Guide has been approved by the U.S. Food and Drug Administration.
2-agonist or LABA for any reason. Other LABA-containing medicines
include ADVAIR DISKUS
® (fluticasone propionate and salmeterol inhalation powder),
SEREVENT
® DISKUS® (salmeterol xinafoate inhalation powder), FORADIL®
AEROLIZER
® (formoterol fumarate inhalation powder), SYMBICORT® (budesonide
and formoterol fumarate dihydrate) Inhalation Aerosol, PERFOROMIST™
(formoterol fumarate) Inhalation Solution, and BROVANA™ (arformoterol tartrate)
Inhalation Solution.
2-agonist medicine with you to treat sudden symptoms. If you do not have an
inhaled, short-acting bronchodilator, contact your healthcare provider to have one
prescribed for you.
ADVAIR® HFA [adv
(fluticasone propionate 45 mcg and salmeterol 21 mcg)
ADVAIR® HFA 115/21 Inhalation Aerosol
(fluticasone propionate 115 mcg and salmeterol 21 mcg)
ADVAIR® HFA 230/21 Inhalation Aerosol
(fluticasone propionate 230 mcg and salmeterol 21 mcg)