Proin: Phenylpropanolamine - Chewable Tablets and Drops for Dogs
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Proin (Phenylpropanolamine) Rx

Due to updated controlled substance requirements, we no longer carry Proin. Please see the end of our Urinary Incontinence in Dogs blog post for an important message about Proin and VetRxDirect.


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When your dog is incontinent it’s uncomfortable for your pet and a messy problem for you. Talk to your veterinarian about Proin, a prescription medication for treating urinary incontinence. Proin reduces leakage by tightening the bladder sphincter muscle.

  • Manages urinary incontinence in dogs
  • Tightens the bladder sphincter muscle to control urine leakage
  • Choose easy dosing liquid or chewable tablets

Age, disease, urinary stones, and even injury can cause a dog to loose complete control over her bladder. When that happens even a housetrained pet may dribble urine or loose large amounts of  urine suddenly. If your dog has urinary incontinence, prescription Proin may help.  The active ingredient in Proin, phenylpropanolamine, is a type of stimulant that causes the muscles in the bladder to contract therefore reducing urine leakage. Given over time, Proin keeps a constant level of phenylpropanolamine in the blood so your dog will have more bladder control. Note: Proin is classified as a controlled substance in our home state of Iowa, so prescriptions for Proin are only valid for six months. We must obtain a new prescription from your veterinarian every six months. Refill requests that exceed six months from the prescription date are not valid for this medication.

What you should know about Proin:

  • Talk to your veterinarian before using this product.
  • Follow dosing directions exactly - don’t give your pet more medication than directed and don’t skip doses.
  • Read the label carefully for information about storage, possible side effects, and drug interactions.

For additional information about Proin, click the “More Information” and “Package Insert” tabs above. 

You can find a Client Information Sheet which provides a summary of information about Proin by following the link below:


If you have questions or concerns about Proin Chewable Tablets and Drops for Dogs, or conditions related to its use, contact your pet's veterinarian or pharmacist.


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You can find package inserts which provides more detailed information on Proin's indications, forms of administration, and side effects along with other clinical information by following the links below.
Proin Package Inserts do not take the place of instructions from your veterinarian. Talk to your veterinarian if you do not understand any of the information provided in these documents or if you have more questions about Proin for Dogs.
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