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This product is a refrigerated item and $19.99 OVERNIGHT SHIPPING IS REQUIRED.
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Leukeran® (chlorambucil) Tablets for Pets
Why has my veterinarian prescribed Leukeran Tablets?
Chlorambucil is prescribed to suppress the immune system and to treat abnormal tissue growth that may be benign or cancerous. This drug may be used for other conditions including: lymphocytic leukemia, multiple myeloma, glomerulonephritis, non-erosive arthritis, immune-mediated skin disease, feline pemphigus foliaceous, and severe feline eosinophilic granuloma complex.
How do I give Leukeran Tablets?
First, READ THE LABEL CAREFULLY.
Give Chlorambucil to your pet as directed by your veterinarian.
Wear gloves when handling this medication.
Avoid contact with your pet's urine, feces, and saliva for 48 hours after each dose.
Wash your hands after administering this medication.
Try to give this medication at the same time(s) each day.
DO NOT give your pet more medicine than directed.
DO NOT give your pet medicine more often than prescribed.
DO NOT stop giving this medication unless directed by your veterinarian.
Try not to miss giving any doses.
If I miss a dose, what do I do?
If you miss a dose, give it to your pet as soon as possible. If it is almost time for the next dose, skip the missed dose, then continue with the regular dosing schedule. Do not give your pet two doses at once
How do I store Leukeran Tablets?
Keep this medicine out of reach of children and pets.
Store this medicine in a tight, light resistant container in your refrigerator at 2- 8° C.
What are the potential side effects of Leukeran Tablets?
While your pet is on this medication, your veterinarian will probably monitor your pet's blood levels regularly to check for bone marrow suppression, which may result in anemia or bleeding disorders. These symptoms may appear one to two weeks after initiating therapy. Contact your veterinarian if you notice that your pet is experiencing bruising, bleeding, excessive tiredness, infection, depression or difficulty breathing.
Some dogs may lose their hair after treatment with this medication.
Chlorambucil can increase your pet's chance of getting an infection, so try to keep your pet away from stray animals or animals that may have an infection.
Other side effects may occur. If you notice anything unusual, contact your veterinarian.
What about possible drug interactions?
Be sure to tell your veterinarian about any other medications you are giving to your pet.
It’s not uncommon for your veterinarian to prescribe two different medications, which may cause a drug interaction to occur. If this happens, your veterinarian may change the dose and/or monitor your pet more closely.
The following drugs may interact with Chlorambucil: other neoplastic agents, other bone marrow depressant drugs, and other immunosuppressant drugs.
Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.
Chlorambucil (Rx) Tablets for Pets
Trade Names:
Chlorambucil is a potent drug used in the treatment of some types of cancer. It is also used as an immunosuppressant in some conditions where this is desired.
- An immunosuppressive agent
- Given by mouth
- Used in the treatment of certain types of cancer in dogs and cats (ex. lymphocytic leukemia, multiple myeloma, ovarian cancer, lymphoma)
- Used in immune mediated conditions where an immunosuppressant drug can be helpful (ex. pemphigus, inflammatory bowel disease, feline infectious peritonitis, immune-mediated hemolytic anemia)
- Pregnant pets
- Pets with pre-existing bone marrow suppression, those already immune suppressed (ex. FIV positive cats), or those with chronic infections
- Fertility can be affected permanently in young pets
- If your pet has had an allergic reaction to chlorambucil or like products
Read and follow the label carefully. Wear gloves when handling this medication.
Give the exact amount prescribed and only as often as directed.
As an immunosuppressant: It is usually given once a day or once every other day.
As a cancer drug: It is usually given once a day or once every other day or every 2-3 weeks.
Give this medication for as long as veterinarian directs. Do not skip doses or stop giving the medication without consulting your veterinarian.
Baseline blood work to assess your pet's health before starting this drug is recommended. Periodic blood work to monitor its effect is also advised if long-term therapy is necessary.
Call ahead for refills.
If a dose is missed, give it as soon as you can. If it is time already for the next dose, skip the missed dose and go back to the normal schedule. Do not give two doses at the same time.
Talk to your veterinarian about:
- When will your pet need to be rechecked
- What tests may need to be performed prior to and during treatment with this drug
- What are the risks and benefits of using this drug
Tell your veterinarian about:
- If your pet has experienced side-effects on other drugs/products
- If your pet has experienced digestive upset now or ever
- If your pet has experienced liver or kidney disease now or ever
- If your pet has experienced any other medical problems or allergies now or ever
- All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet's medicines can be given together.
- If your pet is pregnant or nursing or if you plan to breed your pet
Store in a tight, light resistant, childproof container in the refrigerator.
Wear gloves while handling this medication as it can cause side effects in humans. Pregnant women should not handle this drug.
Children may be attracted to the sugar-coating on the pill's exterior. Be sure to keep this and all medication out of reach of children and pets.
For 48 hours after each dose, avoid all contact with your pet's urine, feces, saliva or vomitus. Waste should be disposed of in a sealed plastic bag.
Call your physician immediately if you accidentally take this product.
- One or two weeks after starting therapy, if you notice bruising, bleeding, lethargy, infection or if your pet has difficulty breathing, it may be due to anemia or a bleeding disorder (a side effect due to bone marrow suppression). Notify your veterinarian if you notice any of these signs.
- Poodles, Kerry Blues and other breeds may lose their hair. Delayed hair re-growth from shaved areas is possible.
- Possible GI effects and skin rash
- Liver failure, respiratory problems and gout have been reported
- If these symptoms persist or you notice anything else unusual, contact your veterinarian
- Yes, but possible interactions may occur with allopurinol, amphotericin B, azathioprine, chloramphenicol, colchicine, corticosteroids or cyclophosphamide
- If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian.
Contact your veterinarian immediately if pet receives more than the prescribed amount.
Notify your veterinarian if your animal's condition does not improve or worsens despite this treatment.
As with all prescribed medicines, chlorambucil should only be given to the pet for which it was prescribed. It should be given only for the condition for which it was prescribed.
This is just a summary of information about chlorambucil. If you have any questions or concerns about chlorambucil or the condition it was prescribed for, contact your veterinarian.