K9 Advantix® II 

Imidacloprid + Permethrin + Pyriproxyfen for Dogs

Imidacloprid + Permethrin + Pyriproxyfen for Dogs is a topical insecticidal agent used in dogs once a month to kill and repel fleas, ticks, mosquitoes, biting flies and chewing lice. After application, 98-100% of fleas will be killed within 12 hours. Imidacloprid + Permethrin + Pyriproxyfen for Dogs is applied to the skin on the dog’s back every 30 days. Dogs should be greater than 7 weeks of age. It is important to note that this product should only be used on dogs. Imidacloprid + Permethrin + Pyriproxyfen for Dogs is available in 4 sizes (based upon body weight).

• Imidacloprid + Permethrin + Pyriproxyfen for Dogs is an insecticidal agent
• Imidacloprid + Permethrin + Pyriproxyfen for Dogs is applied topically once a month

• Repels and kills all life stages of fleas and ticks, including Deer ticks (vector of Lyme disease), American dog ticks (vector of Rocky Mountain spotted fever), Brown dog ticks (vector of Ehrlichiosis), Lone Star ticks (vector of Ehrlichiosis) for up to four weeks
• Also repels mosquitoes and biting flies and kills chewing lice
• Waterproof

• DO NOT USE ON CATS OR ANY ANIMAL OTHER THAN DOGS
• Puppies less than 7 weeks of age
• Consult your veterinarian before using on older, debilitated, pregnant or nursing dogs
• Pets known to have had an allergic reaction to imidacloprid, permethrin, pyriproxyfen or like products

Be sure to follow the dosage instructions provided by your veterinarian. If you have difficulty applying the medication, contact your veterinarian.
Holding applicator tube in upright position, pull cap off tube. Turn the cap around and place the end of cap back on the tube. Twist the cap to break the seal, then remove cap from tube.
For easier application, ensure that your dog is standing. Using the applicator tip, part the hair to expose the skin. Apply the contents of the tube evenly in two to four spots on the top of the back from the shoulder to the base of the tail. To prevent run-off, do not apply an excessive amount at any one spot.
Use the entire contents of the tube that correctly corresponds with the body weight of your dog. Use only one tube per treatment.
Do not allow pets to lick the product or ingest in any way. If you have multiple pets, keep them separated for a short time to prevent licking. Repeat application monthly. Mark your calendar with the dates of subsequent treatments.
After applying this product to your pet, wash your hands with soap and water. Small children should avoid handling the treated dog for a day or two.
For external use only. Do NOT give by mouth. Keep the product away from your dog's eyes and mouth
Reinfesting fleas are killed within 2 hours with protection against further flea infestation lasting at least 4 weeks. Pre-existing pupae in the environment may continue to emerge for 6 weeks or longer depending upon the climatic conditions.
Larval flea stages in the dog’s surroundings are killed following contact with a Imidacloprid + Permethrin + Pyriproxyfen- treated dog.
Waterproof and remains effective following a shampoo treatment, swimming or after exposure to rain or sunlight.
Monthly treatments are required for optimal control and prevention of fleas and ticks.
Read and follow the label carefully.

If a dose is missed, apply it as soon as you can and resume the monthly dosing schedule. Do not give two doses at the same time.

• What tests may need to be performed prior to and during treatment with this drug
• What are the risks and benefits are of using this drug

• If your pet has experienced side-effects on other drugs/products
• If your pet has experienced any other medical problems or allergies now or ever
• All medicines and supplements including flea and tick products that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet's medicines can be given together.
• If your pet is pregnant, nursing or if you plan to breed your pet

For external use on dogs only. Do not get this product in dog's eyes or mouth.
Due to their unique physiology and inability to metabolize certain compounds, this product must not be used on cats. If applied to a cat, or ingested by a cat which actively grooms a recently treated dog, this product may have serious harmful effects. If this occurs, contact your veterinarian immediately.
Store in a cool, dry place. Protect from freezing.
Causes eye irritation. Harmful if swallowed. Do not get in the eyes or on clothing. Avoid contact with skin. Wash hands thoroughly with soap and water after handling.
People should not use this product. Keep this and all medication out of reach of children and pets. Call your physician immediately if you accidentally take this product.
Do not contaminate water or food by storage or disposal. Do not re-use empty container. Securely wrap original container in several layers of newspaper and discard in trash.

• Individual sensitivities may occur with any pesticide product. If they occur, consult your veterinarian immediately. If signs persist, or become more severe, consult a veterinarian immediately.

Yes, but ensure that your veterinarian knows of all of the medicines and supplements that you are giving or planning on giving to your pet.
If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian.

In case of overdose, contact your veterinarian immediately or call 1-800-422-9874.

Notify your veterinarian if your animal's condition does not improve or worsens despite this treatment.

As with all prescribed medicines, Imidacloprid + Permethrin + Pyriproxyfen for Dogs should only be applied to the dog for which it was prescribed.

This is just a summary of information about Imidacloprid + Permethrin + Pyriproxyfen for Dogs. If you have any questions or concerns about Imidacloprid + Permethrin + Pyriproxyfen for Dogs, or for the condition(s) it was prescribed, contact your veterinarian.

Every effort has been made to ensure the accuracy of the information published. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the USA product label or package insert.

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K9 ADVANTIX^® II

Bayer Animal Health

READ THE ENTIRE LABEL BEFORE EACH USE

DO NOT USE ON CATS

For the Prevention and Treatment of Ticks, Fleas, Mosquitoes, Biting Flies and Lice on Dogs

• Repels and kills ticks including Deer ticks (vector of Lyme disease), American dog ticks (vector of Rocky Mountain spotted fever), Brown dog ticks (vector of Ehrlichiosis), and Lone Star ticks (vector of Ehrlichiosis) for up to four weeks

• Repels and kills all life stages of fleas

• Prevents fleas on treated dogs from infesting your home

• Kills fleas on dogs within 12 hours and continues to prevent infestations for a month

• Prevents development of fleas, flea eggs, pupae and larvae for a month

• Larval flea stages in the dog’s surroundings are killed following contact with a K9 Advantix^® II treated dog

• Repels and kills mosquitoes for up to four weeks

• Repels and prevents blood-feeding by biting flies

• Waterproof

• 5-way protection against ticks, fleas, mosquitoes, biting flies and lice

• Kills chewing lice

Active Ingredients	% By Weight
Imidacloprid	8.80%
Permethrin*	44.00%
Pyriproxyfen	0.44%
Other Ingredients	46.76%
Total	100.0%

*cis/trans ratio: max 55% (±) cis and min 45% (±) trans

KEEP OUT OF REACH OF CHILDREN

WARNING

See below for First Aid and Precautionary Statements.

PRECAUTIONARY STATEMENTS

HAZARDS TO HUMANS

Causes substantial but temporary eye injury. Do not get in eyes or on clothing. Harmful if swallowed. Avoid contact with skin or clothing. Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum, or using tobacco. Remove and wash contaminated clothing before reuse.

HAZARDS TO DOMESTIC ANIMALS

For external use on dogs only. Do not use on animals other than dogs. Do not use on puppies under seven weeks of age.

Do not get this product in dog’s eyes or mouth. As with any product, consult your veterinarian before using this product on debilitated, aged, pregnant or nursing animals. Individual sensitivities, while rare, may occur after using ANY pesticide product for pets. If signs persist, or become more severe, consult a veterinarian immediately. If your animal is on medication, consult your veterinarian before using this or any other product.

DO NOT USE ON CATS Due to their unique physiology and inability to metabolize certain compounds, this product must not be used on cats. If applied to a cat, or ingested by a cat which actively grooms a recently treated dog, this product may have serious harmful effects. If this occurs, contact your veterinarian immediately.

For consumer questions call 1-800-255-6826.

For medical emergencies call 1-800-422-9874.

Environmental Hazards

This product is extremely toxic to fish.

Do not add directly to water. Do not contaminate water when disposing of product or packaging.

FIRST AID

Have the product container or label with you when calling a poison control center or doctor, or going for treatment.

If in eyes: Hold eye open and rinse slowly and gently with water for 15-20 minutes. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye.

Call a poison control center or doctor for treatment advice.

If swallowed: Call poison control center or doctor immediately for treatment advice. Have person sip a glass of water if able to swallow. Do not induce vomiting unless told to do so by the poison control center or doctor.

Do not give anything by mouth to an unconscious person.

If on skin or clothing: Take off contaminated clothing. Rinse skin immediately with plenty of water for 15-20 minutes. Call a poison control center or doctor for treatment advice.

To Physician: Treat the patient symptomatically.

DIRECTIONS FOR USE

It is a violation of Federal Law to use this product in a manner inconsistent with its labeling. Do not contaminate feed or food.

HOW TO APPLY

1. Use only on dogs.

DO NOT USE ON CATS or on other animals.

2. Remove applicator tube from the package. Use scissors and peel down foil.

3. Hold applicator tube in an upright position. Pull cap off tube.

4. Turn the cap around and place other end of cap back on tube.

5. Twist cap to break seal, then remove cap from tube.

10 lbs. and Under:

11-20 lbs.:

6. The dog should be standing for easy application. The entire contents of the K9 Advantix^® II tube should be applied evenly to two to three spots on the top of the back from the shoulder to the base of the tail. At each spot, part the hair until the skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of the dog.

21-55 lbs.:

Over 55 lbs.:

6. The dog should be standing for easy application. The entire contents of the K9 Advantix^® II tube should be applied evenly to four to six spots on the top of the back from the shoulder to the base of the tail. At each spot, part the hair until the skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of the dog.

7. Discard empty tube as described in Storage and Disposal.

The successive feeding activity of fleas on dogs may elicit a hypersensitivity skin disorder known as flea allergy dermatitis (FAD). Treatment of dogs with K9 Advantix^® II rapidly kills fleas and may reduce the incidence of this condition.

K9 Advantix^® II kills existing fleas on dogs within 12 hours. Reinfesting fleas are killed within 2 hours with protection against further flea infestation lasting at least four (4) weeks. Pre-existing pupae in the environment may continue to emerge for six (6) weeks or longer depending upon the climatic conditions.

Larval flea stages in the dog’s surroundings are killed following contact with a K9 Advantix^® II treated dog.

K9 Advantix^® II is waterproof and remains effective following a shampoo treatment, swimming or after exposure to rain or sunlight.

Monthly treatments are required for optimal control and prevention of fleas and ticks.

If re-treatment becomes necessary, do not re-treat more than once every week.

STORAGE AND DISPOSAL

Do not contaminate water, food or feed by storage or disposal.

Storage: Store in a cool, dry place. Protect from freezing.

Disposal: Nonrefillable container.

If empty: Do not reuse this container.

Place in trash or offer for recycling, if available.

If partly filled: Call your local solid waste agency or 1-800-422-9874 for disposal instructions. Never place unused product down any indoor or outdoor drain.

Limited Warranty and Limitation of Damages

Bayer HealthCare LLC, Animal Health Division warrants that this material conforms to the chemical description on the label.

TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER MAKES NO OTHER EXPRESS OR IMPLIED WARRANTY, INCLUDING ANY OTHER EXPRESS OR IMPLIED WARRANTY OF FITNESS OR MERCHANTABILITY, and no agent of Bayer is authorized to do so except in writing with a specific reference to this warranty. To the extent consistent with applicable law, any damages arising from a breach of this warranty shall be limited to direct damages and shall not include consequential commercial damages such as loss of profits or values, etc.

Manufactured For

Bayer HealthCare LLC, Animal Health Division, P.O. Box 390, Shawnee Mission, Kansas 66201 USA

Bayer, the Bayer Cross and K9 Advantix^® II are registered trademarks of Bayer

© 2010 Bayer HealthCare LLC

Made in Germany

K9 Advantix^® II is protected by the following U.S. patents: 6,232,328 and other patents pending

K9 ADVANTIX II Small Dog

79147554 - Four 0.014 fl oz (0.4 mL) Tubes	83000628/04458455/04458463, R.0
79147554 - Six 0.014 fl oz (0.4 mL) Tubes

EPA Est. No. 11556-DEU-1 EPA Reg. No. 11556-141

K9 ADVANTIX II Medium Dog

79147953 - Four 0.034 fl oz (1.0 mL) Tubes	83000644/04458498/04461618, R.0
79147953 - Six 0.034 fl oz (1.0 mL) Tubes

EPA Est. No. 11556-DEU-1 EPA Reg. No. 11556-142

K9 ADVANTIX II Large Dog

79148097 - Four 0.084 fl oz (2.5 mL) Tubes	83000660/04461626/04461634, R.0
79148097 - Six 0.084 fl oz (2.5 mL) Tubes

EPA Est. No. 11556-DEU-1 EPA Reg. No. 11556-143

K9 ADVANTIX II Extra Large Dog

79148232 - Four 0.135 fl oz (4.0 mL) Tubes	83000687/04461642/04461650, R.0
79148232 - Six 0.135 fl oz (4.0 mL) Tubes

EPA Est. No. 11556-DEU-1 EPA Reg. No. 11556-144

Regulations for product use are established by country. Information contained on this site pertains only to the United States of America, and is not intended to provide adequate information for product use. Before using or dispensing any product, read and carefully observe the label directions.