Vetadryl: Diphenhydramine for Veterinary Use - VetRxDirect
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Vetadryl (Diphenhydramine) Antihistamine Tablets for Pets

If your pet suffers from seasonal allergies, motion sickness or anxiety talk to your veterinarian about Vetadryl, an over-the-counter antihistamine that eases allergy symptoms and has a sedative affect that calms cats and dogs.

  • Eases allergies, motion sickness, travel anxiety, and discomfort due to insect bites
  • Contains diphenhydramine
  • For dogs and cats
  • Flavored tablets available in two dosage levels


Versatile Vetadryl is an antihistamine recommended by veterinarians to treat a range of issues including allergies, motion sickness, travel anxiety – even insect bites that cause itching and pain. The active ingredient in Vetadryl is diphenhydramine. This chemical blocks the histamines that cause allergic reactions such as itching, watery eyes, runny noses and swelling. One side effect of the histamine blocking process is sleepiness, which is why this medication also works to calm pets and reduce motion sickness. Talk to your veterinarian about whether Vetadryl is right for your pet’s condition. Vetadryl is available in 10 and 30 mg flavored tablets. Have a question about Vetadryl? Click on the “Ask A Question” tab above.


What you should know about Vetadryl:

  • Talk to your veterinarian before using this product.
  • Follow dosing directions exactly - don’t give your pet more medication than directed and don’t skip doses.
  • Read the label carefully for information about storage, possible side effects, and drug interactions.


For additional information about Vetadryl, click the “More Information” and “Package Insert” tabs above.

You can find a Client Information Sheet which provides a summary of information about Diphenhydramine hydrochloride, the active ingredient in Vetadryl, by following the link below:

Diphenhydramine Client Information Sheet*


If you have questions or concerns about Diphenhydramine, or conditions related to its use, contact your pet's veterinarian or pharmacist.


*This link opens in a new window.

You can find a package insert which provides more detailed information on Vetadryl Flavored Tablets' indications, forms of administration, and side effects, along with other clinical information, by following the links below:

Vetadryl 10mg Tablets Package Insert*

Vetadryl 30mg Tablets Package Insert*


Vetadryl's Package Insert does not take the place of instructions from your veterinarian. Talk to your veterinarian if you do not understand the information provided in these documents or if you have any questions about Vetadryl Diphenhydramine HCl Tablets for Veterinary Use.


*This link opens in a new window.