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Tylosin (Compounded) Rx

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Tylosin (Compounded) Antibiotic for Dogs and Cats


Why has my pet's veterinarian prescribed Tylosin (Compounded) Antibiotic for Dogs and Cats?

Tylosin is a macrolide antibiotic similar to erythromycin. This medicine is active against gram-positive and gram-negative bacteria, spirochetes, Chlamydophila, and Mycoplasma organisms. Tylosin is usually prescribed to treat certain types of diarrhea in dogs and cats. It may also be used to treat bronchitis, tracheobronchitis, laryngitis, tonsillitis, pneumonia, rhinitis, sinusitis, cellulitis, and ear infections. Tylosin is also prescribed to treat inflammation of the urinary bladder, uterus, endometrium, and of the skin.  


How do I give Tylosin (Compounded) Antibiotic for Dogs and Cats?


  • Give Tylosin to your pet as directed by your pet's veterinarian.
  • Give this medicine to your pet for as long as prescribed by your pet's veterinarian, even if your pet seems to be feeling better. This will help to ensure the infection is completely cleared up.
  • Give this medicine to your pet with food.
  • DO NOT give your pet more medicine than directed.
  • DO NOT give your pet medicine more often than prescribed.
  • Try not to miss giving any doses.



If I miss a dose, what do I do?

If you miss a dose, give it to your pet as soon as possible. If it is almost time for the next dose, skip the missed dose, then continue with the regular dosing schedule. Do not give your pet two doses at once.


How do I store Tylosin (Compounded) Antibiotic for Dogs and Cats?

Keep this medicine out of reach of children.


Store capsules, liquid, and powder at room temperature in a dry, cool place. Keep this medicine away from heat and direct sunlight.


Do not store this medicine in damp places, in the bathroom, or near the kitchen sink. This medication can break down when exposed to moisture or heat.


What are the potential side effects of Tylosin (Compounded) Antibiotic for Dogs and Cats?         

Tylosin may cause mild stomach upset, lack of appetite, and diarrhea. If these symptoms continue, contact your pet's veterinarian.


Occasionally diarrhea worsens initially before it improves.


Other side effects can occur. If you notice anything unusual, contact your pet's veterinarian.


What about possible drug interactions?

Be sure to tell your pet's veterinarian about any other medications or supplements you are giving your pet.


It’s not uncommon for your pet's veterinarian to prescribe two different medications, which may cause a drug interaction to occur. If this happens, your pet's veterinarian may change the dose and/or monitor your pet more closely.


Drug interactions with Tylosin have not been well documented. However, digitalis is known to interact with Tylosin.


Contact your pet's veterinarian if your pet experiences any unusual reactions when different medications are given together.


You can find a Client Information Sheet which provides a summary of information about Tylosin by following the link below:


Tylosin Client Information Sheet*


If you have questions or concerns about Compounded Tylosin for Pets, or conditions related to its use, contact your pet's veterinarian or pharmacist.


*This link opens in a new window.

Referencing Tylan's (active ingredient tylosing) package label may be beneficial to you before giving tylosin to your pet.

You can find a package label which provides more detailed information on Tylan 100's indications, forms of administration, and side effects, along with other clinical information, by following the link below:


Tylan 100 Package Label*


Tylan 100's package label does not take the place of instructions from your pet's veterinarian. Talk to your pet's veterinarian or pharmacist if you do not understand the information provided in this document or if you have any questions about Compounded Tylosin for dogs and cats.


*This link opens in a new window.

Do you have questions about this product?

Get answers from real customers and in-house experts with AnswerBox.

3 Questions | 3 Answers
Displaying questions 1-3
  • Q:

    Can I open the capsules and give it as a powder if I can't get him to take it
    Asked on 4/30/2015 by leo s from central square new york

    1 answer

    • A:

      You can open the capsule and sprinkle over the pet’s food, but tylosin has a naturally bitter taste and may not be well accepted by your pet. If you are having a hard time getting your pet to take tylosin, talk to your veterinarian about other options for administration or if there are other agents available for pet’s condition.

      Thank you,

      Answered on 6/5/2015 by VetRxDirect
  • Q:

    I need 15 capsules of TYLOSINE 25 mg/kg for my rescued greyhound.
    Asked on 1/27/2014 by Winstin from Saqn Diego

    1 answer

    • A:

      Orders can be placed through our website at any time. As Tylosin is a prescription medication, you will be required to create an account and include your greyhound's information as well as the veterinarian information. Once you've placed your order, we will send a request to your dog's veterinarian requesting approval for the prescription. If your dog's veterinarian does not fax prescriptions, they may opt to give you a written prescription which you can then mail to us. After we receive the prescription, the order would go to compounding to be made, and then shipped out.

      If you have any difficulty placing your order or any additional questions, you can contact us at 866-761-6578 and a technician would be happy to talk you through the order process.

      Thank you,

      Answered on 1/29/2014 by VetRxDirect from VetRxDirect
  • Q:

    Can these capsules be open to put directly on food? Also, I have this for my dog in a jar and my vet precribed 1 1/2 teaspoon 2x day with food. Would these capsules be equal to 1 1/2 teaspoon per capsule? Thanks so much.Sincerely,Jeanne
    Asked on 8/8/2013 by Jeanne

    1 answer

    • A:


      Tylosin may be spread over food to mask the bitterness of the medication, however the whole dose of the medication and therefore the entire meal must be eaten in order for the dog to receive the whole dose. Be careful because the medication is very bitter so it's common for pets to stop eating before the whole dose is consumed. Also, it is important if you choose to add the medication to water rather than food, then water should be added to the dose of powder rather than the powder being added into the water.

      Unfortunately, we are unable to equate 340mg capsules with 1.5 teaspoons of powder since we do not know how much weight of medication is held in teaspoons. However, it may be helpful to know the compounded capsules contain only 340mg of Tylosin with no added inactive ingredients.

      We recommend to use the dose for your dog out of the jar as recommended by your dog's veterinarian or to order the size capsules (in mg) as prescribed by your pet's veterinarian.

      Thank you,


      Answered on 8/10/2013 by VetRxDirect
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Compounded by VetRxDirectTylosin (Compounded)

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    Comments about Compounded by VetRxDirect Tylosin (Compounded):

    We had Tylosin compounded as my dog wouldnt take the plain powder. Well, this must still be bitter, because she hates this too (she takes other meds just fine). Would be nice if it could be flavored. It does the job, but giving it is still a chore.

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