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Trilostane (Compounded) Rx

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Compounded Trilostane for the Treatment of Cushing’s Disease in Dogs

Beyond Use Date:

  • Capsules: It is recommended that this product be used within 6 months.
  • Suspension: It is recommended that this product be used within 3 months.

 

To provide the freshest product possible, VetRxDirect prepares our compounded medications as directed after we receive prescription authorization from your veterinarian.  Occasionally, this may add an additional day or two to our shipping terms.  We appreciate your understanding of this policy. 
Order online today or please call or e-mail VetRxDirect's compounding pharmacist at 866-761-6578 or info@vetrxdirect.com if your veterinarian has prescribed any variation from the listed dose strengths or quantities of this compounded medication.

Compounded Trilostane Capsules

What are trilostane capsules:

Trilostane is a medication used to treat Cushing’s Disease, or hyperadrenocorticism. Cushing’s Disease is a disorder where the body produces too much cortisol. This is a product that contains the medication, trilostane, in a capsule formulation.

What else should you know about compounded trilostane capsules:

Trilostane capsules are compounded by VetRxDirect’s expert compounding staff. They are available in many dosage forms to tailor to your pet’s needs. The capsules need to be stored away from humidity, light, and heat.  It is important to order your refills a few days ahead of time because the product needs to be made for your pet. Trilostane capsules have an expiration date of 6 months after they are made, so pay close attention to expiration dates on your label. Quantities and charges ordered exceeding the beyond use date will be adjusted to hopefully prevent your pet’s medication from expiring before they are finished.

What strengths of compounded trilostane capsules are available:

This particular product is available in 31 various capsule strengths. You may also get other strengths if your veterinarian prescribes them and we will specially make them for your pet. There are also some inactive ingredients contained in the capsule to make the formula complete.

 

Compounded Trilostane Oral Suspension

What is trilostane suspension.

Trilostane is a medication used to treat Cushing’s Disease, or hyperadrenocorticism. Cushing’s Disease is a disorder where the body produces too much cortisol.  This is a product that contains the medication, trilostane, in a liquid suspension formulation given by mouth.

What else should you know about compounded trilostane liquid:

Trilostane suspensions are compounded by our expert compounding staff at VetRxDirect. It is important to order your refills a few days ahead of time because the product needs to be made for your pet. Shake the suspension well before each time you draw up your pet’s dose. Trilostane suspensions expire 3 months from the date they are made, so pay close attention to the expiration dates on your label. Quantities and charges ordered exceeding the beyond use date will be adjusted to hopefully prevent your pet’s medication from expiring before they are finished.

What strengths of compounded trilostane liquid are available:

There are 11 various strengths available of trilostane suspensions, all of which are beef flavored.  You may also get other strengths or flavors if your veterinarian prescribes them and we will specially make them for your pet.

 

You can find a Client Information Sheet which provides a summary of information about Compounded Trilostane for Dogs by following the link below:

Trilostane Client Information Sheet*

 

If you have questions or concerns about Trilostane, or conditions related to its use, contact your pet's veterinarian or pharmacist.

 

*This link opens in a new window.

Prescription Trilostane is proven effective at easing the symptoms of Cushing’s Disease, also known as hyperadrenocorticism. Dogs with this disease produce too much of the hormone cortisol. Trilostane regulates cortisol production in the adrenal gland. The right dosage amount is critical to effective treatment, which is why we compound Trilostane in dozens of strengths and two different formulations.

  •  Controls cortisol production
  •  Helps manage the adrenal-dependent and pituitary-dependent forms of Cushing’s Disease
  •  Reduces symptoms
  •  Compounded in dozens of strengths to match your dog’s needs
  •  Two formulations – convenient capsules or beef flavored liquid

 

Many dogs with Cushing’s Disease require a daily dose of Trilostane to regulate cortisol levels in their blood. Our compounding pharmacy makes giving your pet that critical daily dose more effective and easier. While Trilostane is commercially available in only four capsule strengths, we compound it into dozens of strengths to closely match your dog’s specific needs. We also offer the medication in capsules or beef flavored liquid for easy dosing. Administering Trilostane daily will help regulate the cortisol levels in your dog’s bloodstream and will reduce symptoms of the disease over time.

 

What you should know about Compounded Trilostane:

  •  Talk to your veterinarian before using this product.
  •  Follow dosing directions exactly - don’t give your pet more medication than directed and don’t skip doses.
  •  Read the label carefully for information about storage, possible side effects, and drug interactions.
 

Do you have questions about this product?

Get answers from real customers and in-house experts with AnswerBox.

7 Questions | 7 Answers
Displaying questions 1-7
  • Q:

    Can the oral suspension of Trilostane cause teeth deterioration? I've noticed since I've been giving my 93# dog the medicine since the end of October, his teeth have gotten quite brown. Gums are red as well. They were pretty white prior.
    Asked on 12/21/2014 by Balloo from Bainbridge Island, WA, United States

    1 answer

    • A:

      The most common adverse effects seen with trilostane use are lethargy, weakness, loss of appetite for a fews day, vomiting and diarrhea. I am unable to find any medical literature associating teeth or tongue discoloration or deterioration with the use of trilostane. I recommend contacting your veterinarian to determine the cause of this.

      Thank you,
      VetRxDirect

      Answered on 12/26/2014 by VetRxDirect from VetRxDirect
  • Q:

    My 11 year old 54 lb dog has been on a 2 x daily dosage of 0.5 liquid trilostane for 17 days.  She is still exhibiting symptoms of Cushings including excessive drinking, urination, panting at rest and increased appetite. How long before she improves?
    Asked on 9/1/2014 by Gracie11 from Glendale, AZ, United States

    1 answer

    • A:

      Trilostane is a common treatment for dogs with high cortisol levels or Cushing’s disease. The starting dose of the medication is determined by the weight of the pet and then adjusted according to the cortisol levels and clinical symptoms. Cortisol levels are typically checked 10-14 days after beginning treatment and the dose is then adjusted accordingly. Reaching the optimum dose to control symptoms and reduce side effects may take several dose adjustments. It is important to follow up with all appointments. It may be beneficial to contact your veterinarian and report your dogs continued clinical symptoms after 17 days of treatment.

      Thank you,
      VetRxDirect

      Answered on 9/9/2014 by VetRxDirect from VetRxDirect
  • Q:

    The liquid version, should it be refrigerated?
    Asked on 4/8/2014 by janete from Alabama, United States

    1 answer

    • A:

      Janete,

      Trilostane (compounded) liquid should be stored at room temperature in a tightly sealed container. We recommend to use trilostane (compounded) liquid within 90 days of compounding this product. The beyond-use-date or expiration date for the compound will be stated on the bottle.

      Thank you,
      VetRxDirect

      Answered on 4/9/2014 by VetRxDirect
  • Q:

    Do you ship to Australia
    Asked on 11/29/2013 by Jim

    1 answer

    • A:

      Jim,

      Unfortunately, we cannot ship to Australia.  We are licensed to ship within the United States, and for prescription medications, like the trilostane, a prescription from a licensed United States veterinarian is required.

      Thank you,

      VetRxDirect

      Answered on 11/29/2013 by VetRxDirect
  • Q:

    If I have a written prescription from my vet can I fax it to you or does it need to be mailed?
    Asked on 10/18/2013 by Sherry

    1 answer

    • A:

      Sherry,

      Pharmacy law requires that we have the original prescription that the veterinarian issued to you, which means, legally, the prescription would need to be mailed to us.  A scan or a fax of a written prescription is considered a copy and pharmacies are not legally able to accept them.

      We can accept faxes directly from clinics, but it is up to each clinic whether or not they are willing to fax a prescription directly to us.  You may want to check with your clinic.  Many clinics will be unwilling to fax if they have already issued a written prescription, in which case, they may require you to return the prescription to them.

      Thank you,

      VetRxDirect

      Answered on 10/21/2013 by VetRxDirect
  • Q:

    I have a whippet (26lb). At what level of trilostane is to much? My vet been upper her level to 150mg. It's costing me $250 plus blood work for another $250 a month.
    Asked on 9/27/2013 by Selina

    1 answer

    • A:

      Selina,

      For your dog with the weight of 26 pounds (11.8 kg), the standard dose is 60 mg every 24 hours and may be adjusted based on cortisol levels (taken from blood work).  If your dog is being treated for alopecia, the dose might be upwards to 150 mg.  Please discuss your questions and concerns with your veterinarian to determine the problem being treated as well as why the dose continues to increase.

      Thank you,

      VetRxDirect

      Answered on 9/30/2013 by VetRxDirect
  • Q:

    What are the pros and cons of the suspension vs. the capsule form of trilostane? I believe that the capsule (powdered) form has a slightly longer shelf life, but are there other differences? Thank you.
    Asked on 9/16/2013 by Matt

    1 answer

    • A:

      Matt,

      You are correct that the capsules are good for 6 months and the suspension is good for 3 months.  The capsules are already dosed out whereas the beef flavored suspension has to be measured from the bottle for each dose.  The capsule, however, should not be opened and might make it harder for the animal to take versus the suspension.  There are pros and cons of both, so it is important to discuss with your veterinarian which option might be better for your pet.

      Thank you,

      VetRxDirect

      Answered on 9/18/2013 by VetRxDirect
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Compounded by VetRxDirectTrilostane (Compounded)
 
4.9

(based on 27 reviews)

Ratings Distribution

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    (24)

  • 4 Stars

     

    (3)

  • 3 Stars

     

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Reviewed by 27 customers

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5.0

Great service. Fast shipping.

By 

from Hermosa, SD

Verified Buyer

Comments about Compounded by VetRxDirect Trilostane (Compounded):

Great product. Fast shipping.

  • Was this a gift?:
  • No
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5.0

Works Great

By 

from Burbank, Ca

Verified Buyer

Pros

  • Fast delivery
  • Get exact pill dose
  • Good communication with Vet

Cons

  • None

Best Uses

    Comments about Compounded by VetRxDirect Trilostane (Compounded):

    We have been ordering this for my dog from Vetrxdirect for years. We would have lost our Nikita if we did not have the compounded blend for her. Thank you so much.

    We have heard of other places that our friends have tried but they have had complications. We have had zero complications.

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    • No
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    5.0

    Fast Service

    By 

    from Boston Ma

    Verified Buyer

    Comments about Compounded by VetRxDirect Trilostane (Compounded):

    Great service and fast shipping.

    • Was this a gift?:
    • No
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    5.0

    I plan to buy this product from you, as needed....thank you.

    By 

    from Chiefland, Florida

    Verified Buyer

    Comments about Compounded by VetRxDirect Trilostane (Compounded):

    My dog has cushings disease...and is a diabetic....it is difficult to get the dose he needs of Trilostane, and at any time may have to be changed, either up or down. I am happy with your service.

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    5.0

    Best Price Best Quality

    By 

    from New Orleans

    Verified Buyer

    Pros

    • Afforadble
    • Coupon Codes Available
    • Excellent Quality
    • Speedy Delivery
    • Wonderful Customer Service

    Cons

      Best Uses

        Comments about Compounded by VetRxDirect Trilostane (Compounded):

        Most affordable compounded quality medication for our dog. Couldn't ask for better service and product!

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        5.0

        Best pharmacy for pet meds

        By 

        from North Carolina

        Verified Buyer

        Comments about Compounded by VetRxDirect Trilostane (Compounded):

        I have been using VetRx for about three years. Thank goodness for VetRx, I could not afford the trilostane from other pharmacies. My Jax has cushings disease.

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        5.0

        I will buy this product again.

        By 

        from Florida

        Verified Buyer

        Pros

          Cons

            Best Uses

            • Compounded service

            Comments about Compounded by VetRxDirect Trilostane (Compounded):

            Needed for pet healyhn

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            4.0

            trilostane compounded results

            By 

            from Silver Spring

            Verified Buyer

            Comments about Compounded by VetRxDirect Trilostane (Compounded):

            Trade brand used 30mgs for good control. Tried compounded@ 35. Didn't work well. Had to go to 45mg to equivent of trade brand. All based on required testing results. Advise to test to insure right dosage.

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            5.0

            Trilostane Compound Is A Miracle!

            By 

            from Wilton, CT USA

            Verified Buyer

            Comments about Compounded by VetRxDirect Trilostane (Compounded):

            Our 11 pound diabetic Silky Terrier was not being "managed" with insulin shots. Her vet did not give much hope but said she could have Cushings Disease and to try Trilostane. She was on it for two days when blood glucose testing indicated the insulin dose should be dropped! Can't wait to see what her bg test shows next week. We are on a ROLL toward good health for Sadie!!!

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            (1 of 1 customers found this review helpful)

             
            5.0

            Thank you for keeping my dog alive!!!!

            By 

            from North Carolina

            Verified Buyer

            Comments about Compounded by VetRxDirect Trilostane (Compounded):

            I could not afford the trilostane with other pharmacies. I appreciate the discount, it helps so much. The customer service is always great. I tell everybody about VetRx. I will use you forever. Carolyn Moore

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