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Trilostane (Compounded) Rx

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Compounded Trilostane for the Treatment of Cushing’s Disease in Dogs

Beyond Use Date:

  • Capsules: It is recommended that this product be used within 6 months.
  • Suspension: It is recommended that this product be used within 3 months.

 

To provide the freshest product possible, VetRxDirect prepares our compounded medications as directed after we receive prescription authorization from your veterinarian.  Occasionally, this may add an additional day or two to our shipping terms.  We appreciate your understanding of this policy. 
Order online today or please call or e-mail VetRxDirect's compounding pharmacist at 866-761-6578 or info@vetrxdirect.com if your veterinarian has prescribed any variation from the listed dose strengths or quantities of this compounded medication.

Compounded Trilostane Capsules

What are trilostane capsules:

Trilostane is a medication used to treat Cushing’s Disease, or hyperadrenocorticism. Cushing’s Disease is a disorder where the body produces too much cortisol. This is a product that contains the medication, trilostane, in a capsule formulation.

What else should you know about compounded trilostane capsules:

Trilostane capsules are compounded by VetRxDirect’s expert compounding staff. They are available in many dosage forms to tailor to your pet’s needs. The capsules need to be stored away from humidity, light, and heat.  It is important to order your refills a few days ahead of time because the product needs to be made for your pet. Trilostane capsules have an expiration date of 6 months after they are made, so pay close attention to expiration dates on your label. Quantities and charges ordered exceeding the beyond use date will be adjusted to hopefully prevent your pet’s medication from expiring before they are finished.

What strengths of compounded trilostane capsules are available:

This particular product is available in 31 various capsule strengths. You may also get other strengths if your veterinarian prescribes them and we will specially make them for your pet. There are also some inactive ingredients contained in the capsule to make the formula complete.

 

Compounded Trilostane Oral Suspension

What is trilostane suspension.

Trilostane is a medication used to treat Cushing’s Disease, or hyperadrenocorticism. Cushing’s Disease is a disorder where the body produces too much cortisol.  This is a product that contains the medication, trilostane, in a liquid suspension formulation given by mouth.

What else should you know about compounded trilostane liquid:

Trilostane suspensions are compounded by our expert compounding staff at VetRxDirect. It is important to order your refills a few days ahead of time because the product needs to be made for your pet. Shake the suspension well before each time you draw up your pet’s dose. Trilostane suspensions expire 3 months from the date they are made, so pay close attention to the expiration dates on your label. Quantities and charges ordered exceeding the beyond use date will be adjusted to hopefully prevent your pet’s medication from expiring before they are finished.

What strengths of compounded trilostane liquid are available:

There are 11 various strengths available of trilostane suspensions, all of which are beef flavored.  You may also get other strengths or flavors if your veterinarian prescribes them and we will specially make them for your pet.

 

You can find a Client Information Sheet which provides a summary of information about Compounded Trilostane for Dogs by following the link below:

Trilostane Client Information Sheet*

 

If you have questions or concerns about Trilostane, or conditions related to its use, contact your pet's veterinarian or pharmacist.

 

*This link opens in a new window.

Prescription Trilostane is proven effective at easing the symptoms of Cushing’s Disease, also known as hyperadrenocorticism. Dogs with this disease produce too much of the hormone cortisol. Trilostane regulates cortisol production in the adrenal gland. The right dosage amount is critical to effective treatment, which is why we compound Trilostane in dozens of strengths and two different formulations.

  •  Controls cortisol production
  •  Helps manage the adrenal-dependent and pituitary-dependent forms of Cushing’s Disease
  •  Reduces symptoms
  •  Compounded in dozens of strengths to match your dog’s needs
  •  Two formulations – convenient capsules or beef flavored liquid

 

Many dogs with Cushing’s Disease require a daily dose of Trilostane to regulate cortisol levels in their blood. Our compounding pharmacy makes giving your pet that critical daily dose more effective and easier. While Trilostane is commercially available in only four capsule strengths, we compound it into dozens of strengths to closely match your dog’s specific needs. We also offer the medication in capsules or beef flavored liquid for easy dosing. Administering Trilostane daily will help regulate the cortisol levels in your dog’s bloodstream and will reduce symptoms of the disease over time.

 

What you should know about Compounded Trilostane:

  •  Talk to your veterinarian before using this product.
  •  Follow dosing directions exactly - don’t give your pet more medication than directed and don’t skip doses.
  •  Read the label carefully for information about storage, possible side effects, and drug interactions.
 

Do you have questions about this product?

Get answers from real customers and in-house experts with AnswerBox.

7 Questions | 7 Answers
Displaying questions 1-7
  • Q:

    Can the oral suspension of Trilostane cause teeth deterioration? I've noticed since I've been giving my 93# dog the medicine since the end of October, his teeth have gotten quite brown. Gums are red as well. They were pretty white prior.
    Asked on 12/21/2014 by Balloo from Bainbridge Island, WA, United States

    1 answer

    • A:

      The most common adverse effects seen with trilostane use are lethargy, weakness, loss of appetite for a fews day, vomiting and diarrhea. I am unable to find any medical literature associating teeth or tongue discoloration or deterioration with the use of trilostane. I recommend contacting your veterinarian to determine the cause of this.

      Thank you,
      VetRxDirect

      Answered on 12/26/2014 by VetRxDirect from VetRxDirect
  • Q:

    My 11 year old 54 lb dog has been on a 2 x daily dosage of 0.5 liquid trilostane for 17 days.  She is still exhibiting symptoms of Cushings including excessive drinking, urination, panting at rest and increased appetite. How long before she improves?
    Asked on 9/1/2014 by Gracie11 from Glendale, AZ, United States

    1 answer

    • A:

      Trilostane is a common treatment for dogs with high cortisol levels or Cushing’s disease. The starting dose of the medication is determined by the weight of the pet and then adjusted according to the cortisol levels and clinical symptoms. Cortisol levels are typically checked 10-14 days after beginning treatment and the dose is then adjusted accordingly. Reaching the optimum dose to control symptoms and reduce side effects may take several dose adjustments. It is important to follow up with all appointments. It may be beneficial to contact your veterinarian and report your dogs continued clinical symptoms after 17 days of treatment.

      Thank you,
      VetRxDirect

      Answered on 9/9/2014 by VetRxDirect from VetRxDirect
  • Q:

    The liquid version, should it be refrigerated?
    Asked on 4/8/2014 by janete from Alabama, United States

    1 answer

    • A:

      Janete,

      Trilostane (compounded) liquid should be stored at room temperature in a tightly sealed container. We recommend to use trilostane (compounded) liquid within 90 days of compounding this product. The beyond-use-date or expiration date for the compound will be stated on the bottle.

      Thank you,
      VetRxDirect

      Answered on 4/9/2014 by VetRxDirect
  • Q:

    Do you ship to Australia
    Asked on 11/29/2013 by Jim

    1 answer

    • A:

      Jim,

      Unfortunately, we cannot ship to Australia.  We are licensed to ship within the United States, and for prescription medications, like the trilostane, a prescription from a licensed United States veterinarian is required.

      Thank you,

      VetRxDirect

      Answered on 11/29/2013 by VetRxDirect
  • Q:

    If I have a written prescription from my vet can I fax it to you or does it need to be mailed?
    Asked on 10/18/2013 by Sherry

    1 answer

    • A:

      Sherry,

      Pharmacy law requires that we have the original prescription that the veterinarian issued to you, which means, legally, the prescription would need to be mailed to us.  A scan or a fax of a written prescription is considered a copy and pharmacies are not legally able to accept them.

      We can accept faxes directly from clinics, but it is up to each clinic whether or not they are willing to fax a prescription directly to us.  You may want to check with your clinic.  Many clinics will be unwilling to fax if they have already issued a written prescription, in which case, they may require you to return the prescription to them.

      Thank you,

      VetRxDirect

      Answered on 10/21/2013 by VetRxDirect
  • Q:

    I have a whippet (26lb). At what level of trilostane is to much? My vet been upper her level to 150mg. It's costing me $250 plus blood work for another $250 a month.
    Asked on 9/27/2013 by Selina

    1 answer

    • A:

      Selina,

      For your dog with the weight of 26 pounds (11.8 kg), the standard dose is 60 mg every 24 hours and may be adjusted based on cortisol levels (taken from blood work).  If your dog is being treated for alopecia, the dose might be upwards to 150 mg.  Please discuss your questions and concerns with your veterinarian to determine the problem being treated as well as why the dose continues to increase.

      Thank you,

      VetRxDirect

      Answered on 9/30/2013 by VetRxDirect
  • Q:

    What are the pros and cons of the suspension vs. the capsule form of trilostane? I believe that the capsule (powdered) form has a slightly longer shelf life, but are there other differences? Thank you.
    Asked on 9/16/2013 by Matt

    1 answer

    • A:

      Matt,

      You are correct that the capsules are good for 6 months and the suspension is good for 3 months.  The capsules are already dosed out whereas the beef flavored suspension has to be measured from the bottle for each dose.  The capsule, however, should not be opened and might make it harder for the animal to take versus the suspension.  There are pros and cons of both, so it is important to discuss with your veterinarian which option might be better for your pet.

      Thank you,

      VetRxDirect

      Answered on 9/18/2013 by VetRxDirect
Displaying questions 1-7

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Compounded by VetRxDirectTrilostane (Compounded)
 
4.9

(based on 14 reviews)

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Reviewed by 14 customers

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5.0

Fast, reliable service with good follow-up

By 

from San Antonio, TX, USA

Verified Buyer
Site Member

Comments about Compounded by VetRxDirect Trilostane (Compounded):

My 10-year old Maltapoo recently was diagnosed with Cushings disease; she was prescribed 5mgTrilostane BID. The medication arrived promptly and Sophie is having a positive response: less compulsive water consumption and less frequent urination (less accidents). I was impressed with VetRxDirect's service and prices.

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4.0

Good product

By 

from Austin, TX, USA

Verified Buyer
Site Member

Comments about Compounded by VetRxDirect Trilostane (Compounded):

Return customer and process is easy. Just make sure you order a week in advance. Turn around time is not very fast

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5.0

Great company! Best deal on trilostane!

By 

from New Jersey, USA

Verified Buyer
Site Member

Comments about Compounded by VetRxDirect Trilostane (Compounded):

My dog sammie needed 90 mg of Trilostane twice a day. The pills are not generally available in this strength so I had to purchase 60 and 30 mg pills separately. Before I found Vetrxdirect, the medication was costing me over $300.00 a month. Vetrxdirect is able to compound the medication for me in the required 90 mg dosage per pill. I am saving over $100.00 a month with Vetrxdirect. They are very professional. Ordering and shipping is fast and easy. They contact my Vet directly for refills, saving me time. The medication to treat my Sammies Cushings disease is so expensive so I am very thankful for the savings I am getting from Vetrxdirect. I also get Thyroid medication for Sammie and my other dog Trapper at a substantial savings. I would recommend Vetrxdirect to anyone.

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5.0

Compounded Trilostane works well

By 

from Micco, FL

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Site Member

Comments about Compounded by VetRxDirect Trilostane (Compounded):

3 days after starting, Sage had an ACTH blood test. First time she has been close to the correct number.
We are so happy. We will be using VetRxDirect for a long time.

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5.0

excellent company to buy from

By 

from Fairfield, CA, USA

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Comments about Compounded by VetRxDirect Trilostane (Compounded):

I searched the Web, and this was the only company that carried the dosage of Trilostane my beagle needs for her cushing's. Ordering is easy, and they contact my vet directly. I have been very happy with their product, and how it continues to help my pet live a longer, happier life.

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5.0

Great Price Value + Service!!!

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from Cape Coral, FL, USA

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Comments about Compounded by VetRxDirect Trilostane (Compounded):

Vet RX Direct has been compounding a prescription drug for our dog, Mollie, since 2010. We have always found Vet RX Direct to be courteous and prompt. Our dogs always look forward to the box arriving because they know a dog treat will be inside.

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5.0

Meds have helped my 4-legged son, Jackson!

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from North Carolina, USA

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Comments about Compounded by VetRxDirect Trilostane (Compounded):

Jackson (my dog) has a chronic condition that requires this medicine. I'm grateful it has improved his overall health and well-being. We can tell he feels so much better! You would never know his 9 years old-full of energy and overflowing personality.

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5.0

Always in stock.

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from Tracy, CA, USA

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Comments about Compounded by VetRxDirect Trilostane (Compounded):

My dog is reliant on daily medication. VetRx always has his medication in stock

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5.0

working well

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from NY, NY

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Comments about Compounded by VetRxDirect Trilostane (Compounded):

My dog was put on 10mg of Vetoryl for Cushings and it was not working well for him. He would get very tired and spacey and there was no change in his profuse urination. The 5 mg doses twice a day are making a big difference and I'm very happy we were able to get this dosage compounded.

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5.0

Trilostane (For treatment of Cushings)

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from Palm Beach, FL, USA

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Comments about Compounded by VetRxDirect Trilostane (Compounded):

My Papillon was diagnosed with Cushings and will be on this medicine for the rest of his life. VetRX service is excellent and this med is effective. Note that this is the generic, saving $.

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