Cestex (epsiprantel) Tablets for the removal of tapeworms in the cat and dog.
INDICATIONS AND USAGE: Cestex tablets are indicated for the removal of the following:
Feline cestodes: Dipylidium caninum and Taenia taeniaeformis
Canine cestodes: Dipylidium caninum and Taenia pisiformis
CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Epsiprantel is an oral anthelmintic (dewormer) used to kill tapeworms in dogs and cats. This medication kills the types of tapeworms your pet may contract from fleas or rodents. Tablets may be crumbled or mixed in the food. Fasting is not necessary. Four different strengths of film-coated tablets are available.
What is this product?- An anthelmintic (dewormer) for dogs and cats
- Given by mouth
- To kill the common tapeworm (2 types) in dogs and cats
- Use with caution in pregnant and nursing dogs and cats
- Puppies and kittens less than 7 weeks of age
- If your pet has had an allergic reaction to epsiprantel or like products before
Read and follow the label carefully.
Fasting is not necessary prior nor recommended.
Tablets may be given with or without food.
Ensure that your pet swallows all of the medication.
A single treatment should be sufficient, but pets will need another dose if re-infected. Re-infection will occur if there is a heavy, uncontrolled flea problem or if your pet eats mice or rabbits.
Tapeworms are always acquired by ingesting an infected intermediate host (flea, dog louse, rabbit, rodent, uncooked beef/lamb/pork/venison/fish/wild animals).
Ensure that fleas are eliminated from your pet’s environment and do not allow your pet to eat uncooked meat/fish.
To maximize the benefit of deworming, it is best to treat all animals in the environment. Periodic fecal exams are recommended to monitor effectiveness and re-exposure to parasites.
Some intestinal parasites can infect humans. Strict hygienic precautions should be observed when handling infected pets and their feces. Consult your veterinarian or family doctor to discuss how to prevent human infection and re-infection of your pet.
Epsiprantel is given as a single dose.
What to tell/ask veterinarian before giving this medication?Talk to your veterinarian about:
- When your pet will need to be rechecked
- What tests may need to be performed prior to and during treatment with this drug
- What are the risks and benefits of using this drug
Tell your veterinarian about:
- If your pet has experienced side-effects on other drugs/products
- If your pet has experienced digestive upset now or ever
- If your pet has experienced any other medical problems or allergies now or ever
- If your pet is pregnant or nursing or if you plan to breed your pet
- Store in a tight, light resistant, childproof container in a cool, dry place at room temperature away from heat and direct sunlight.
- Not for human use. Keep this and all medication out of reach of children and pets.
- Call your physician immediately if you accidentally take this product.
- Side effects are rare, but at high doses, vomiting or diarrhea may occur
- If you notice anything unusual, contact your veterinarian
- Yes, there are no known drug interactions, but if your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian
Contact your veterinarian immediately if pet receives more than the prescribed amount.
What else should I know?Notify your veterinarian if your animal's condition does not improve or worsens despite this treatment.
As with all prescribed medicines, epsiprantel should only be given to the pet for which it was prescribed. It should be given only for the condition for which it was prescribed.
This is just a summary of information about epsiprantel. If you have any questions or concerns about epsiprantel or the condition it was prescribed for, contact you
| Every effort has been made to ensure the accuracy of the information published. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the USA product label or package insert. |
CESTEX®
Pfizer Animal Health
(epsiprantel)
Veterinary Tablets
Cestex (epsiprantel) tablets are indicated for the removal of tapeworms in the cat (Dipylidium caninum and Taenia taeniaeformis) and dog (Dipylidium caninum and Taenia pisiformis).
CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian.
DESCRIPTION: Cestex tablets are film-coated and contain 12.5 mg, 25 mg, 50 mg or 100 mg of epsiprantel per tablet.
Epsiprantel is an anthelmintic that is active as a single dose against the common tapeworms of cats and dogs. Epsiprantel has a molecular weight of 326 and is chemically 2-(cyclohexylcarbonyl)-4-oxo-1,2,3,4,6,7,8,12b-octahydropyrazino[2,1-a][2]benza-zepine. It is a stable white solid which is sparingly soluble in water. Its chemical structure is presented below.
Action: Epsiprantel acts directly on the tapeworm. Since it is minimally absorbed following oral administration, epsiprantel remains at the site of action within the gastrointestinal tract. Due to digestive process, tapeworm fragments or proglottids may not be readily visible in the stool.
INDICATIONS AND USAGE: Cestex tablets are indicated for the removal of the following:
Feline cestodes: Dipylidium caninum and Taenia taeniaeformis
Canine cestodes: Dipylidium caninum and Taenia pisiformis
CONTRAINDICATIONS: There are no known contraindications to the use of this drug.
WARNINGS: For use in cats and dogs only. Safety of use in pregnant or breeding animals has not been determined. Keep out of reach of children. Not for use in humans.
PRECAUTION: Do not use in kittens or puppies less than 7 weeks of age.
DOSAGE AND ADMINISTRATION: Cestex tablets should be administered orally.
The recommended dosage of epsiprantel is: cats, 1.25 mg/lb of body weight; dogs, 2.5 mg/lb of body weight. The following table may be used as a guide:
Dosage Schedule
Feline
|
Body Weight |
Dose |
|
Seven weeks old |
|
|
up to 10 lb |
12.5 mg |
|
11-20 lb |
25.0 mg |
Canine
|
Body Weight |
Dose |
|
Seven weeks old |
|
|
up to 5 lb |
12.5 mg |
|
6-10 lb |
25.0 mg |
|
11-20 lb |
50.0 mg |
|
21-40 lb |
100.0 mg |
|
41-50 lb |
125.0 mg |
|
51-60 lb |
150.0 mg |
|
61-80 lb |
200.0 mg |
|
81-90 lb |
225.0 mg |
|
91-100 lb |
250.0 mg |
|
101+ lb |
2.5 mg/lb, rounding up to next whole tablet combination |
Fasting is not necessary or recommended.
Unless exposure to the infected intermediate hosts is controlled, reinfection is likely and retreatment may be required. In the case of D. caninum, an effective flea control program should be instituted.
SAFETY: Epsiprantel has been evaluated in cats at 5 times the recommended dose given once daily for 3 days with no adverse effects noted. In tolerance studies, epsiprantel produced minimal clinical signs in cats given 40 times the recommended dose once daily for 4 days.
Epsiprantel has been evaluated in 14-day repeat dose studies in dogs at 500 mg/kg (90 times recommended dosage) with no significant adverse results. No side effects were observed during the clinical field studies.
Epsiprantel is not a cholinesterase inhibitor. During the course of clinical field studies, Cestex was administered concurrently with diethylcarbamazine citrate (dogs only), anti-inflammatory agents, insecticides, and nematocides with no drug incompatibilities noted.
STORAGE: Store at controlled room temperature 15°-30°C (59°-86°F).
HOW SUPPLIED: Cestex tablets are film-coated and contain 12.5 mg, 25 mg, 50 mg or 100 mg of epsiprantel per tablet. Cestex is supplied as described below:
|
Concentration |
Weight (lbs) |
Number Tablets/Bottle |
|
|
Cat |
Dog |
||
|
12.5 mg |
10 |
5 |
50, 100 |
|
25.0 mg |
20 |
10 |
50, 100 |
|
50.0 mg |
- - |
20 |
25, 50 |
|
100.0 mg |
- - |
40 |
25, 50 |
NADA #140-893, Approved by FDA
Distributed by: Pfizer Animal Health, Div. of Pfizer Inc, NY, NY 10017
MADE IN INDIA
75-8032-10IN01
December 2007