Allopurinol is used for the prevention of urate bladder stone in dogs.
Allopurinol Generic Tablets for Dogs
Why has my veterinarian prescribed this medicine?
Allopurinol is used to prevent the recurrence of uric acid stones. The medicine works by decreasing the amount of uric acid in the body. This medication has also been recommended as an alternative treatment for Leishmaniasis in dogs.
How do I give this medication?
- Give this medication to your pet as directed by your veterinarian. READ THE LABEL CAREFULLY.
- Give this medication 1 hour after meals, unless otherwise directed by your veterinarian.
- Have water available for your pet to drink.
- If the medicine is a liquid, measure the dose with reasonable care.
- Try to give this medication at about the same time each day.
- DO NOT give the pet more medicine than directed and do not give more often than directed.
- Try not to miss giving any doses.
What if I miss giving a dose?
Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give the pet two doses at once.
How do I store this medicine?
- Keep this medicine out of reach of children.
- Store this medicine in a cool, dry place at room temperature. Store away from heat and direct sunlight.
- Do not store this medicine in the bathroom, near the kitchen sink or in damp places. The medicine may break down if exposed to heat or moisture.
What are the potential side effects?
"Notify your veterinarian if your pet develops a rash, becomes very tired or ill."
- Adverse effects in dogs are uncommon.
- Notify your veterinarian if your pet develops a rash, becomes very tired or ill.
- The drug should be used with caution in dogs with decreased kidney function.
- Notify your veterinarian if side effects are noted and they are troublesome.
- Other side effects may occur. If you notice anything unusual, contact your veterinarian.
Are there any possible drug interactions?
- Make sure to tell your veterinarian if you are giving your pet any other medication or supplements.
- Quite often, your veterinarian may prescribe two different medications, and sometimes a drug interaction may be anticipated. If this occurs, your veterinarian may vary the dose and/or monitor your pet more closely.
- The following drugs can potentially interact with allopurinol: cyclophosphamide, probenecid, sulfinpyrazone, methionine, ammonium chloride, amoxicillin, hetacillin, ampicillin, azathioprine, mercaptopurine, furosemide, thiazides, diazoxide, trimethoprim / sulfamethoxazole, warfarin, aminophyllin, and theophyllin.
- Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.
Allopurinol (Generic) Tablets for Pets
Trade Names:
Zyloprim
Zyloric General Description:
This drug inhibits an enzyme resulting in a decrease in the amount of uric acid produced in the body. Allopurinol is available in tablets.
What is this drug?- A xanthine oxidase inhibitor
- Given by mouth
- To prevent formation of urate bladder stones
- An alternative treatment for Leishmania and Trypanosoma parasites
- Animals with liver or kidney disease
- Animals that may be pregnant or nursing
- Animals with a known hypersensitivity or allergy to this drug should not take this medication
Read and follow the prescription label carefully.
Give the exact amount prescribed and only as often as directed.
Give this medication for as long as your veterinarian directs. Do not skip doses or stop giving the medication without consulting your veterinarian.
Baseline blood work and urinalysis are recommended to assess your pet's general health before starting this drug.
Periodic blood work and follow-up urinalysis are required to monitor allopurinol's effect on the body as long-term therapy is often necessary.
Dose adjustments may be made based upon these results and an assessment of how your dog or cat is responding clinically.
Call ahead for refills.
Ideally, give medication at the same time(s) daily.
This medication is often given in conjunction with a low purine diet to avoid formation of other bladder stones.
What if a dose is missed?If a dose is missed, give it as soon as you can. If it is time already for the next dose, skip the missed dose and go back to the normal schedule. Do not give two doses at the same time.
What to tell/ask a veterinarian before giving medication?Talk to your veterinarian about:
- When your pet will need to be rechecked
- What tests may need to be performed prior to and during treatment with this drug
- What are the risks and benefits of using this drug
Tell your veterinarian about:
- If your pet has experienced side-effects on other drugs/products
- If your pet has experienced digestive upset now or ever
- If your pet has experienced liver or kidney disease now or ever
- If your pet has experienced any other medical problems or allergies now or ever
- All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet's medications can be given together.
- If your pet is pregnant, nursing or if you plan to breed your pet
Allopurinol should be stored in a childproof container in a cool, dry place at room temperature away from heat and direct sunlight.
Keep this and all medication out of reach of children and pets.
Call your physician immediately if you accidentally take this product.
Potential side effects:Chronic use of this medication without proper attention to diet can cause xanthine bladder stones and possible difficulty with urinating
This medication can affect the gastrointestinal system causing nausea, vomiting, cramping, and diarrhea
This medication can affect the liver
This medication can affect the skin causing hives, itchiness, or a rash
This medication can cause bone marrow suppression
If these symptoms persist or you notice anything else unusual, contact your veterinarian
Yes, but possible interactions may occur when giving allopurinol in conjunction with: certain diets, aminophylline, ammonium chloride, amoxicillin, ampicillin, azathioprine, cyclophosphamide, furosemide, methionine, theophylline, trimethoprim/sulfas, and oral anticoagulants like warfarin
Drugs other than those listed may also interact with allopurinol
Do not give new food or medications without first talking to your veterinarian
If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian
Contact your veterinarian immediately if your pet receives more than the prescribed amount.
What else should I know?Notify your veterinarian if your animal's condition does not improve or worsens despite this treatment.
As with all prescribed medicines, allopurinol should only be given to the pet for which it was prescribed.
It should be given only for the condition for which it was prescribed.
This is just a summary of information about allopurinol. If you have any questions or concerns about allopurinol or the condition it was prescribed for, please contact your veterinarian.